RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammat...
RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNF[alpha] or anti-IL-1 therapies
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BioMed Central Ltd
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English
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BioMed Central Ltd
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Introduction Rat adjuvant-induced arthritis (AIA) and collagen-induced arthritis (CIA) feature bone loss and systemic increases in TNF[alpha], IL-1[beta], and receptor activator of NF-[kappa]B ligand (RANKL). Anti-IL-1 or anti-TNF[alpha] therapies consistently reduce inflammation in these models, but systemic bone loss often persists. RANKL inhibit...
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RANKL inhibition by osteoprotegerin prevents bone loss without affecting local or systemic inflammation parameters in two rat arthritis models: comparison with anti-TNF[alpha] or anti-IL-1 therapies
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TN_cdi_gale_infotracacademiconefile_A216654333
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_gale_infotracacademiconefile_A216654333
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1478-6354
DOI
10.1186/ar2879
