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XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03234079v1

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

About this item

Full title

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

Publisher

New York: Nature Publishing Group US

Journal title

Nature Medicine, 2021-06, Vol.27 (6), p.1043-1054

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of life-threatening cirrhosis, liver failure and liver cancer. Chronic necro-inflammation is a critical factor in development of NASH, yet the cellular and molecular mechanisms of immune dysregulation in th...

Alternative Titles

Full title

XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_hal_primary_oai_HAL_hal_03234079v1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03234079v1

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X,1744-7933

DOI

10.1038/s41591-021-01344-3

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