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Both MAPK and STAT3 signal transduction pathways are necessary for IL-6-dependent hepatic stellate cells activation
Author / Creator:Kagan, Polina ; Sultan, Maya ; Tachlytski, Irina ; Safran, Michal ; Ben-Ari, Ziv
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-05, Vol.12 (5), p.e0176173-e0176173
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XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Author / Creator:Deczkowska, Aleksandra ; David, Eyal ; Ramadori, Pierluigi ; Pfister, Dominik ; Safran, Michal ; Li, Baoguo ; Giladi, Amir ; Jaitin, Diego Adhemar ; Barboy, Oren ; Cohen, Merav ; Yofe, Ido ; Gur, Chamutal ; Shlomi-Loubaton, Shir ; Henri, Sandrine ; Suhail, Yousuf ; Qiu, Mengjie ; Kam, Shing ; Hermon, Hila ; Lahat, Eylon ; Ben Yakov, Gil ; Cohen-Ezra, Oranit ; Davidov, Yana ; Likhter, Mariya ; Goitein, David ; Roth, Susanne ; Weber, Achim ; Malissen, Bernard ; Weiner, Assaf ; Ben-Ari, Ziv ; Heikenwälder, Mathias ; Elinav, Eran ; Amit, Ido
Publisher:New York: Nature Publishing Group US
Journal title:Nature Medicine, 2021-06, Vol.27 (6), p.1043-1054
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Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production
Author / Creator:Gotlieb, Neta ; Tachlytski, Irena ; Lapidot, Yelena ; Sultan, Maya ; Safran, Michal ; Ben-Ari, Ziv
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2018-10, Vol.24 (1), p.53-53, Article 53
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Interleukin-1α and Interleukin-1β play a central role in the pathogenesis of fulminant hepatic failure in mice
Author / Creator:Sultan, Maya ; Ben-Ari, Ziv ; Masoud, Rula ; Pappo, Orit ; Harats, Dror ; Kamari, Yehuda ; Safran, Michal
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-09, Vol.12 (9), p.e0184084-e0184084
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Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma
Author / Creator:Lapidot, Yelena ; Amir, Amnon ; Nosenko, Rita ; Uzan-Yulzari, Atara ; Veitsman, Ella ; Cohen-Ezra, Oranit ; Davidov, Yana ; Weiss, Peretz ; Bradichevski, Tanya ; Segev, Shlomo ; Koren, Omry ; Safran, Michal ; Ben-Ari, Ziv
Publisher:1752 N St., N.W., Washington, DC: American Society for Microbiology
Journal title:mSystems, 2020-06, Vol.5 (3)
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HIF hydroxylation and the mammalian oxygen-sensing pathway
Author / Creator:Safran, Michal ; Kaelin, Jr, William G
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2003-03, Vol.111 (6), p.779-783
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Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo
Author / Creator:Nardinocchi, Lavinia ; Pantisano, Valentina ; Puca, Rosa ; Porru, Manuela ; Aiello, Aurora ; Grasselli, Annalisa ; Leonetti, Carlo ; Safran, Michal ; Rechavi, Gideon ; Givol, David ; Farsetti, Antonella ; D'Orazi, Gabriella
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-12, Vol.5 (12), p.e15048-e15048
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Publisher Correction: XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Author / Creator:Deczkowska, Aleksandra ; David, Eyal ; Ramadori, Pierluigi ; Pfister, Dominik ; Safran, Michal ; Li, Baoguo ; Giladi, Amir ; Jaitin, Diego Adhemar ; Barboy, Oren ; Cohen, Merav ; Yofe, Ido ; Gur, Chamutal ; Shlomi-Loubaton, Shir ; Henri, Sandrine ; Suhail, Yousuf ; Qiu, Mengjie ; Kam, Shing ; Hermon, Hila ; Lahat, Eylon ; Ben Yakov, Gil ; Cohen-Ezra, Oranit ; Davidov, Yana ; Likhter, Mariya ; Goitein, David ; Roth, Susanne ; Weber, Achim ; Malissen, Bernard ; Weiner, Assaf ; Ben-Ari, Ziv ; Heikenwälder, Mathias ; Elinav, Eran ; Amit, Ido
Publisher:New York: Nature Publishing Group US
Journal title:Nature Medicine, 2022-01, Vol.28 (1), p.214-214
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Mouse Model for Noninvasive Imaging of HIF Prolyl Hydroxylase Activity: Assessment of an Oral Agent That Stimulates Erythropoietin Production
Author / Creator:Safran, Michal ; Kim, William Y. ; O'Connell, Fionnuala ; Flippin, Lee ; Günzler, Volkmar ; Horner, James W. ; DePinho, Ronald A. ; Kaelin, William G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (1), p.105-110
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ArticlesPeer ReviewedFull Text
Altered A-to-I RNA editing in human embryogenesis
Author / Creator:Shtrichman, Ronit ; Germanguz, Igal ; Mandel, Rachel ; Ziskind, Anna ; Nahor, Irit ; Safran, Michal ; Osenberg, Sivan ; Sherf, Ofra ; Rechavi, Gideon ; Itskovitz-Eldor, Joseph
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-07, Vol.7 (7), p.e41576-e41576
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Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing
Author / Creator:Osenberg, Sivan ; Paz Yaacov, Nurit ; Safran, Michal ; Moshkovitz, Sharon ; Shtrichman, Ronit ; Sherf, Ofra ; Jacob-Hirsch, Jasmine ; Keshet, Gilmor ; Amariglio, Ninette ; Itskovitz-Eldor, Joseph ; Rechavi, Gideon
Publisher:United States: Public Library of Science
Journal title:PloS one, 2010-06, Vol.5 (6), p.e11173-e11173
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ArticlesPeer ReviewedFull Text
Extracellular Vesicular Transmission of miR-423-5p from HepG2 Cells Inhibits the Differentiation of Hepatic Stellate Cells
Author / Creator:Safran, Michal ; Masoud, Rula ; Sultan, Maya ; Tachlytski, Irena ; Chai Gadot, Chofit ; Pery, Ron ; Balint-Lahat, Nora ; Pappo, Orit ; Buzaglo, Nahum ; Ben-Ari, Ziv
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2022-05, Vol.11 (10), p.1715
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ArticlesPeer ReviewedFull Text
Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury
Author / Creator:Hochhauser, Edith ; Lahat, Eylon ; Sultan, Maya ; Pappo, Orit ; Waldman, Maayan ; Sarne, Yosef ; Shainberg, Asher ; Gutman, Mordechai ; Safran, Michal ; Ari, Ziv Ben
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2015-01, Vol.36 (5), p.1971-1981
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Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats
Author / Creator:Greenberger, Shoshana ; Levanon, Erez Y ; Paz-Yaacov, Nurit ; Barzilai, Aviv ; Safran, Michal ; Osenberg, Sivan ; Amariglio, Ninette ; Rechavi, Gideon ; Eisenberg, Eli
Publisher:England: BioMed Central Ltd
Journal title:BMC genomics, 2010-10, Vol.11 (1), p.608-608, Article 608
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Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma
Author / Creator:Lapidot, Yelena ; Amir, Amnon ; Nosenko, Rita ; Uzan-Yulzari, Atara ; Veitsman, Ella ; Cohen-Ezra, Oranit ; Davidov, Yana ; Weiss, Peretz ; Bradichevski, Tanya ; Segev, Shlomo ; Koren, Omry ; Safran, Michal ; Ben-Ari, Ziv
Publisher:1752 N St., N.W., Washington, DC: American Society for Microbiology
Journal title:mSystems, 2020-06, Vol.5 (3)
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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests
Author / Creator:Netanel, Carmit ; Goitein, David ; Rubin, Moshe ; Kleinbaum, Yeruham ; Katsherginsky, Sima ; Hermon, Hila ; Tsaraf, Keren ; Tachlytski, Irina ; Herman, Amir ; Safran, Michal ; Ben-Ari, Ziv
Publisher:United States: Elsevier Inc
Journal title:The American journal of surgery, 2021-07, Vol.222 (1), p.214-219
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Nature of Interaction between Basic Fibroblast Growth Factor and the Antiangiogenic Drug 7,7-(Carbonyl-Bis[Imino- N-Methyl-4,2-Pyrrolecarbonylimino[ N-Methyl-4,2-Pyrrole]-Carbonylimino])-Bis-(1,3-Naph...
Author / Creator:Zamai, Moreno ; Hariharan, Chithra ; Pines, Dina ; Safran, Michal ; Yayon, Avner ; Caiolfa, Valeria R. ; Cohen-Luria, Rivka ; Pines, Ehud ; Parola, Abraham H.
Publisher:United States: Elsevier Inc
Journal title:Biophysical journal, 2002-05, Vol.82 (5), p.2652-2664
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Interleukin-1[alpha] and Interleukin-1[beta] play a central role in the pathogenesis of fulminant hepatic failure in mice
Author / Creator:Sultan, Maya ; Ben-Ari, Ziv ; Masoud, Rula ; Pappo, Orit ; Harats, Dror ; Kamari, Yehuda ; Safran, Michal
Publisher:Public Library of Science
Journal title:PloS one, 2017-09, Vol.12 (9), p.e0184084
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Automated thermal imaging for the detection of fatty liver disease
Author / Creator:Brzezinski, Rafael Y. ; Levin-Kotler, Lapaz ; Rabin, Neta ; Ovadia-Blechman, Zehava ; Zimmer, Yair ; Sternfeld, Adi ; Finchelman, Joanna Molad ; Unis, Razan ; Lewis, Nir ; Tepper-Shaihov, Olga ; Naftali-Shani, Nili ; Balint-Lahat, Nora ; Safran, Michal ; Ben-Ari, Ziv ; Grossman, Ehud ; Leor, Jonathan ; Hoffer, Oshrit
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.15532-15532, Article 15532
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ArticlesPeer ReviewedFull Text
Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivo
Author / Creator:Kim, William Y ; Safran, Michal ; Buckley, Marshall RM ; Ebert, Benjamin L ; Glickman, Jonathan ; Bosenberg, Marcus ; Regan, Meredith ; Kaelin Jr, William G
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2006-10, Vol.25 (19), p.4650-4662
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Both MAPK and STAT3 signal transduction pathways are necessary for IL-6-dependent hepatic stellate cells activation

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XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

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Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production

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Interleukin-1α and Interleukin-1β play a central role in the pathogenesis of fulminant hepatic failure in mice

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Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma

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HIF hydroxylation and the mammalian oxygen-sensing pathway

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Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo

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Publisher Correction: XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis

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Mouse Model for Noninvasive Imaging of HIF Prolyl Hydroxylase Activity: Assessment of an Oral Agent That Stimulates Erythropoietin Production

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Altered A-to-I RNA editing in human embryogenesis

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Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing

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Extracellular Vesicular Transmission of miR-423-5p from HepG2 Cells Inhibits the Differentiation of Hepatic Stellate Cells

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Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury

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Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats

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Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma

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The impact of bariatric surgery on nonalcoholic fatty liver disease as measured using non-invasive tests

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Nature of Interaction between Basic Fibroblast Growth Factor and the Antiangiogenic Drug 7,7-(Carbonyl-Bis[Imino- N-Methyl-4,2-Pyrrolecarbonylimino[ N-Methyl-4,2-Pyrrole]-Carbonylimino])-Bis-(1,3-Naph...

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Interleukin-1[alpha] and Interleukin-1[beta] play a central role in the pathogenesis of fulminant hepatic failure in mice

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Automated thermal imaging for the detection of fatty liver disease

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Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivo

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