Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blind...
Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial
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PRECISION investigators , Bellet, Marc , Bakris, George L , Flack, John M , Wang, Ji-Guang , Schlaich, Markus , Katz, Ivor , Ajani, Andrew , Colquhoun, David , Mooney, John , De Backer, Tine , Persu, Alexandre , Chaumont, Martin , Vanassche, Thomas , Pliamm, Lew , Merali, Fatima , Dresser, George , Vallee, Michel , Jolly, Shivinder , Wang, Jiguang , Mu, Jianjun , Yu, Jing , Yuan, Hong , Zhang, Xin , Xie, Jianhong , Lin, Ling , Soucek, Miroslav , Widimsky, Jiri , Cifkova, Renata , Vaclavik, Jan , Ormezzano, Olivier , Azizi, Michel , Courand, Pierre-Yves , Ott, Christian , Kyfnidis, Konstantinos , Manolis, Athanasios , Patsilinakos, Sotirios , Zebekakis, Pantelis , Karavidas, Apostolos , Denes, Pall , Sukholutsky, Ivetta , Yosefy, Chaim , Kenis, Irina , Maria Lorenza, Muiesan , Taddei, Stefano , Lee, Hae-Young , Raugaliene, Rasa , Kavaliauskiene, Roma , Kroon, Abraham , Januszewicz, Andrzej , Tykarski, Andrzej , Chrostowska, Marzena , Krekora, Jan , Kania, Grzegorz , Podziewski, Maciej , Wilkolaski, Andrzej , Janik-Palazzolo, Marzena , Rewerska, Barbara , Konradi, Aleksandra , Nikolaev, Konstantin , Gorbunov, Vladimir , Obrezan, Andrey , Kuzin, Anatoly , Martínez García, Fernando , Redon, Josep , Oliveras, Anna , Bazylevych, Andriy , Karpenko, Oleksandr , Asanov, Ervin , Gupta, Pankaj , Webb, David , MacLeod, Mary , Peace, Aaron , Arora, Samir , Degarmo, Ronald , Guillen, Mario , Karns, Adam , Paliwal, Yogesh , Butcher, Michael Bain , Calhoun, David , Goldman, Jesse M. , Rashidi, Arash , Haley, William , Lang, Brian , Khanna, Dinesh , Park, Jean , Luna, Blanca , Mussaji, Murtaza , McGinty, John , McGrew, Frank , Bolster, Eric , Kalirao, Paramjit , Dabel, Pascal , Calhoun, Wesley , Gouge, Steven , Warren, Mark , Lawrence, Mary Katherine , El-Shahawy, Mohamed , Mercado, Carlos , Kumar, Jayant and Velasquez-Mieyer, Pedro
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Resistant hypertension is associated with increased cardiovascular risk. The endothelin pathway has been implicated in the pathogenesis of hypertension, but it is currently not targeted therapeutically, thereby leaving this relevant pathophysiological pathway unopposed with currently available drugs. The aim of the study was to assess the blood pre...
Alternative Titles
Full title
Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Bellet, Marc
Bakris, George L
Flack, John M
Wang, Ji-Guang
Schlaich, Markus
Katz, Ivor
Ajani, Andrew
Colquhoun, David
Mooney, John
De Backer, Tine
Persu, Alexandre
Chaumont, Martin
Vanassche, Thomas
Pliamm, Lew
Merali, Fatima
Dresser, George
Vallee, Michel
Jolly, Shivinder
Wang, Jiguang
Mu, Jianjun
Yu, Jing
Yuan, Hong
Zhang, Xin
Xie, Jianhong
Lin, Ling
Soucek, Miroslav
Widimsky, Jiri
Cifkova, Renata
Vaclavik, Jan
Ormezzano, Olivier
Azizi, Michel
Courand, Pierre-Yves
Ott, Christian
Kyfnidis, Konstantinos
Manolis, Athanasios
Patsilinakos, Sotirios
Zebekakis, Pantelis
Karavidas, Apostolos
Denes, Pall
Sukholutsky, Ivetta
Yosefy, Chaim
Kenis, Irina
Maria Lorenza, Muiesan
Taddei, Stefano
Lee, Hae-Young
Raugaliene, Rasa
Kavaliauskiene, Roma
Kroon, Abraham
Januszewicz, Andrzej
Tykarski, Andrzej
Chrostowska, Marzena
Krekora, Jan
Kania, Grzegorz
Podziewski, Maciej
Wilkolaski, Andrzej
Janik-Palazzolo, Marzena
Rewerska, Barbara
Konradi, Aleksandra
Nikolaev, Konstantin
Gorbunov, Vladimir
Obrezan, Andrey
Kuzin, Anatoly
Martínez García, Fernando
Redon, Josep
Oliveras, Anna
Bazylevych, Andriy
Karpenko, Oleksandr
Asanov, Ervin
Gupta, Pankaj
Webb, David
MacLeod, Mary
Peace, Aaron
Arora, Samir
Degarmo, Ronald
Guillen, Mario
Karns, Adam
Paliwal, Yogesh
Butcher, Michael Bain
Calhoun, David
Goldman, Jesse M.
Rashidi, Arash
Haley, William
Lang, Brian
Khanna, Dinesh
Park, Jean
Luna, Blanca
Mussaji, Murtaza
McGinty, John
McGrew, Frank
Bolster, Eric
Kalirao, Paramjit
Dabel, Pascal
Calhoun, Wesley
Gouge, Steven
Warren, Mark
Lawrence, Mary Katherine
El-Shahawy, Mohamed
Mercado, Carlos
Kumar, Jayant
Velasquez-Mieyer, Pedro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_hal_03872267v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_hal_03872267v1
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(22)02034-7
