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ArticlesPeer ReviewedFull Text
Systemic sclerosis
Author / Creator:Denton, Christopher P, Prof ; Khanna, Dinesh, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-10, Vol.390 (10103), p.1685-1699
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New composite endpoint in early diffuse cutaneous systemic sclerosis: revisiting the provisional American College of Rheumatology Composite Response Index in Systemic Sclerosis
Author / Creator:Khanna, Dinesh ; Huang, Suiyuan ; Lin, Celia J F ; Spino, Cathie
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2021-05, Vol.80 (5), p.641-650
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Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis
Author / Creator:Denton, Christopher P ; Ong, Voon H ; Xu, Shiwen ; Chen-Harris, Haiyin ; Modrusan, Zora ; Lafyatis, Robert ; Khanna, Dinesh ; Jahreis, Angelika ; Siegel, Jeffrey ; Sornasse, Thierry
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2018-09, Vol.77 (9), p.1362-1371
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Therapeutic Approaches to Systemic Sclerosis: Recent Approvals and Future Candidate Therapies
Author / Creator:Lescoat, Alain ; Roofeh, David ; Kuwana, Masataka ; Lafyatis, Robert ; Allanore, Yannick ; Khanna, Dinesh
Publisher:New York: Springer US
Journal title:Clinical reviews in allergy & immunology, 2023-06, Vol.64 (3), p.239-261
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Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study
Author / Creator:Coghlan, J Gerry ; Denton, Christopher P ; Grünig, Ekkehard ; Bonderman, Diana ; Distler, Oliver ; Khanna, Dinesh ; Müller-Ladner, Ulf ; Pope, Janet E ; Vonk, Madelon C ; Doelberg, Martin ; Chadha-Boreham, Harbajan ; Heinzl, Harald ; Rosenberg, Daniel M ; McLaughlin, Vallerie V ; Seibold, James R
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2014-07, Vol.73 (7), p.1340-1349
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Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial
Author / Creator:Khanna, Dinesh, Prof ; Denton, Christopher P, Prof ; Jahreis, Angelika, MD ; van Laar, Jacob M, Prof ; Frech, Tracy M, MD ; Anderson, Marina E, FRCP ; Baron, Murray, MD ; Chung, Lorinda, MD ; Fierlbeck, Gerhard, MD ; Lakshminarayanan, Santhanam, MD ; Allanore, Yannick, Prof ; Pope, Janet E, MD ; Riemekasten, Gabriela, Prof ; Steen, Virginia, Prof ; Müller-Ladner, Ulf, Prof ; Lafyatis, Robert, MD ; Stifano, Giuseppina, MD ; Spotswood, Helen, PhD ; Chen-Harris, Haiyin, PhD ; Dziadek, Sebastian, PhD ; Morimoto, Alyssa, PhD ; Sornasse, Thierry, PhD ; Siegel, Jeffrey, MD ; Furst, Daniel E, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-06, Vol.387 (10038), p.2630-2640
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ArticlesPeer ReviewedFull Text
Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile
Author / Creator:Skaug, Brian ; Khanna, Dinesh ; Swindell, William R ; Hinchcliff, Monique E ; Frech, Tracy M ; Steen, Virginia D ; Hant, Faye N ; Gordon, Jessica K ; Shah, Ami A ; Zhu, Lisha ; Zheng, W Jim ; Browning, Jeffrey L ; Barron, Alexander M S ; Wu, Minghua ; Visvanathan, Sudha ; Baum, Patrick ; Franks, Jennifer M ; Whitfield, Michael L ; Shanmugam, Victoria K ; Domsic, Robyn T ; Castelino, Flavia V ; Bernstein, Elana J ; Wareing, Nancy ; Lyons, Marka A ; Ying, Jun ; Charles, Julio ; Mayes, Maureen D ; Assassi, Shervin
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2020-03, Vol.79 (3), p.379-386
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Longitudinal Changes in Quantitative Interstitial Lung Disease on Computed Tomography after Immunosuppression in the Scleroderma Lung Study II
Author / Creator:Goldin, Jonathan G. ; Kim, Grace Hyun J. ; Tseng, Chi-Hong ; Volkmann, Elizabeth ; Furst, Daniel ; Clements, Philip ; Brown, Matt ; Roth, Michael ; Khanna, Dinesh ; Tashkin, Donald P.
Publisher:United States: American Thoracic Society
Journal title:Annals of the American Thoracic Society, 2018-11, Vol.15 (11), p.1286-1295
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Expert consensus on the management of systemic sclerosis-associated interstitial lung disease
Author / Creator:Rahaghi, Franck F. ; Hsu, Vivien M. ; Kaner, Robert J. ; Mayes, Maureen D. ; Rosas, Ivan O. ; Saggar, Rajan ; Steen, Virginia D. ; Strek, Mary E. ; Bernstein, Elana J. ; Bhatt, Nitin ; Castelino, Flavia V. ; Chung, Lorinda ; Domsic, Robyn T. ; Flaherty, Kevin R. ; Gupta, Nishant ; Kahaleh, Bashar ; Martinez, Fernando J. ; Morrow, Lee E. ; Moua, Teng ; Patel, Nina ; Shlobin, Oksana A. ; Southern, Brian D. ; Volkmann, Elizabeth R. ; Khanna, Dinesh
Publisher:England: BioMed Central Ltd
Journal title:Respiratory research, 2023-01, Vol.24 (1), p.6-16, Article 6
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Psychometric validation of the Hand Disability in Systemic Sclerosis-Digital Ulcers (HDISS-DU®) patient-reported outcome instrument
Author / Creator:Mouthon, Luc ; Poiraudeau, Serge ; Vernon, Margaret ; Papadakis, Kelly ; Perchenet, Loïc ; Khanna, Dinesh
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2020-01, Vol.22 (1), p.3-3, Article 3
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How do patients define Raynaud’s phenomenon? Differences between primary and secondary disease
Author / Creator:Murphy, Susan L. ; Lescoat, Alain ; Alore, Mary ; Hughes, Michael ; Pauling, John D. ; Sabbagh, Maya ; Khanna, Dinesh
Publisher:Cham: Springer International Publishing
Journal title:Clinical rheumatology, 2021-04, Vol.40 (4), p.1611-1616
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Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort
Author / Creator:Jaafar, Sara ; Lescoat, Alain ; Huang, Suiyuan ; Gordon, Jessica ; Hinchcliff, Monique ; Shah, Ami A. ; Assassi, Shervin ; Domsic, Robyn ; Bernstein, Elana J. ; Steen, Virginia ; Elliott, Sabrina ; Hant, Faye ; Castelino, Flavia V. ; Shanmugam, Victoria K. ; Correia, Chase ; Varga, John ; Nagaraja, Vivek ; Roofeh, David ; Frech, Tracy ; Khanna, Dinesh
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2021-06, Vol.23 (1), p.170-15, Article 170
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Trajectories of forced vital capacity in patients with systemic sclerosis-associated interstitial lung disease
Author / Creator:Distler, Oliver ; Vonk, Madelon C ; Azuma, Arata ; Mayes, Maureen D. ; Khanna, Dinesh ; Highland, Kristin B. ; Toenges, Gerrit ; Alves, Margarida ; Allanore, Yannick
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2025-03, Vol.27 (1), p.63-5, Article 63
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Relationship between quantitative radiographic assessments of interstitial lung disease and physiological and clinical features of systemic sclerosis
Author / Creator:Tashkin, Donald P ; Volkmann, Elizabeth R ; Tseng, Chi-Hong ; Kim, Hyun J ; Goldin, Jonathan ; Clements, Philip ; Furst, Daniel ; Khanna, Dinesh ; Kleerup, Eric ; Roth, Michael D ; Elashoff, Robert
Publisher:England: Elsevier Limited
Journal title:Annals of the rheumatic diseases, 2016-02, Vol.75 (2), p.374-381
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Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis
Author / Creator:Paul, Souren ; Kaplan, Mark H. ; Khanna, Dinesh ; McCourt, Preston M. ; Saha, Anjan K. ; Tsou, Pei-Suen ; Anand, Mahek ; Radecki, Alexander ; Mourad, Mohamad ; Sawalha, Amr H. ; Markovitz, David M. ; Contreras-Galindo, Rafael
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-11, Vol.13 (1), p.7074-7074, Article 7074
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Impact of lung function decline on time to hospitalisation events in systemic sclerosis-associated interstitial lung disease (SSc-ILD): a joint model analysis
Author / Creator:Kreuter, Michael ; Del Galdo, Francesco ; Miede, Corinna ; Khanna, Dinesh ; Wuyts, Wim A. ; Hummers, Laura K. ; Alves, Margarida ; Schoof, Nils ; Stock, Christian ; Allanore, Yannick
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2022-01, Vol.24 (1), p.19-19, Article 19
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Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis
Author / Creator:Ma, Feiyang ; Tsou, Pei-Suen ; Gharaee-Kermani, Mehrnaz ; Plazyo, Olesya ; Xing, Xianying ; Kirma, Joseph ; Wasikowski, Rachael ; Hile, Grace A. ; Harms, Paul W. ; Jiang, Yanyun ; Xing, Enze ; Nakamura, Mio ; Ochocki, Danielle ; Brodie, William D. ; Pillai, Shiv ; Maverakis, Emanual ; Pellegrini, Matteo ; Modlin, Robert L. ; Varga, John ; Tsoi, Lam C. ; Lafyatis, Robert ; Kahlenberg, J. Michelle ; Billi, Allison C. ; Khanna, Dinesh ; Gudjonsson, Johann E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-01, Vol.15 (1), p.210-17, Article 210
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Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study
Author / Creator:Dalbeth, Nicola ; Jones, Graeme ; Terkeltaub, Robert ; Khanna, Dinesh ; Fung, Maple ; Baumgartner, Scott ; Perez-Ruiz, Fernando
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2019-01, Vol.21 (1), p.8-8, Article 8
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Minimal Clinically Important Differences for the Modified Rodnan Skin Score: Results from the Scleroderma Lung Studies (SLS-I and SLS-II)
Author / Creator:Khanna, Dinesh ; Clements, Philip J. ; Volkmann, Elizabeth R. ; Wilhalme, Holly ; Tseng, Chi-hong ; Furst, Daniel E. ; Roth, Michael D. ; Distler, Oliver ; Tashkin, Donald P.
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2019-01, Vol.21 (1), p.23-9, Article 23
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Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis
Author / Creator:Fox, David A. ; Lundy, Steven K. ; Whitfield, Michael L. ; Berrocal, Veronica ; Campbell, Phillip ; Rasmussen, Stephanie ; Ohara, Ray ; Stinson, Alexander ; Gurrea-Rubio, Mikel ; Wiewiora, Evan ; Spino, Catherine ; Bush, Erica ; Furst, Daniel ; Pillai, Shiv ; Khanna, Dinesh
Publisher:England: BioMed Central Ltd
Journal title:Arthritis research & therapy, 2021-01, Vol.23 (1), p.10-10, Article 10
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Showing 1 to 20 of 184 results

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Systemic sclerosis

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New composite endpoint in early diffuse cutaneous systemic sclerosis: revisiting the provisional American College of Rheumatology Composite Response Index in Systemic Sclerosis

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Therapeutic interleukin-6 blockade reverses transforming growth factor-beta pathway activation in dermal fibroblasts: insights from the faSScinate clinical trial in systemic sclerosis

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Therapeutic Approaches to Systemic Sclerosis: Recent Approvals and Future Candidate Therapies

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Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study

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Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial

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Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile

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Longitudinal Changes in Quantitative Interstitial Lung Disease on Computed Tomography after Immunosuppression in the Scleroderma Lung Study II

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Expert consensus on the management of systemic sclerosis-associated interstitial lung disease

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Psychometric validation of the Hand Disability in Systemic Sclerosis-Digital Ulcers (HDISS-DU®) patient-reported outcome instrument

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How do patients define Raynaud’s phenomenon? Differences between primary and secondary disease

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Clinical characteristics, visceral involvement, and mortality in at-risk or early diffuse systemic sclerosis: a longitudinal analysis of an observational prospective multicenter US cohort

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Trajectories of forced vital capacity in patients with systemic sclerosis-associated interstitial lung disease

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Relationship between quantitative radiographic assessments of interstitial lung disease and physiological and clinical features of systemic sclerosis

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Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis

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Impact of lung function decline on time to hospitalisation events in systemic sclerosis-associated interstitial lung disease (SSc-ILD): a joint model analysis

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Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis

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Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study

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Minimal Clinically Important Differences for the Modified Rodnan Skin Score: Results from the Scleroderma Lung Studies (SLS-I and SLS-II)

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Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis

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