Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma:...
Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial
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Author / Creator
Ascierto, Paolo A, Dr , Del Vecchio, Michele, MD , Robert, Caroline, Prof , Mackiewicz, Andrzej, Prof , Chiarion-Sileni, Vanna, MD , Arance, Ana, MD , Lebbé, Céleste, Prof , Bastholt, Lars, MD , Hamid, Omid, MD , Rutkowski, Piotr, Prof , McNeil, Catriona, MD , Garbe, Claus, Prof , Loquai, Carmen, MD , Dreno, Brigitte, Prof , Thomas, Luc, Prof , Grob, Jean-Jacques, Prof , Liszkay, Gabriella, Prof , Nyakas, Marta, MD , Gutzmer, Ralf, Prof , Pikiel, Joanna, MD , Grange, Florent, MD , Hoeller, Christoph, MD , Ferraresi, Virginia, MD , Smylie, Michael, MD , Schadendorf, Dirk, Prof , Mortier, Laurent, Prof , Svane, Inge Marie, MD , Hennicken, Delphine, MSc , Qureshi, Anila, MD and Maio, Michele, MD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background A phase 2 trial suggested increased overall survival and increased incidence of treatment-related grade 3–4 adverse events with ipilimumab 10 mg/kg compared with ipilimumab 3 mg/kg in patients with advanced melanoma. We report a phase 3 trial comparing the benefit–risk profile of ipilimumab 10 mg/kg versus 3 mg/kg. Methods This r...
Alternative Titles
Full title
Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Del Vecchio, Michele, MD
Robert, Caroline, Prof
Mackiewicz, Andrzej, Prof
Chiarion-Sileni, Vanna, MD
Arance, Ana, MD
Lebbé, Céleste, Prof
Bastholt, Lars, MD
Hamid, Omid, MD
Rutkowski, Piotr, Prof
McNeil, Catriona, MD
Garbe, Claus, Prof
Loquai, Carmen, MD
Dreno, Brigitte, Prof
Thomas, Luc, Prof
Grob, Jean-Jacques, Prof
Liszkay, Gabriella, Prof
Nyakas, Marta, MD
Gutzmer, Ralf, Prof
Pikiel, Joanna, MD
Grange, Florent, MD
Hoeller, Christoph, MD
Ferraresi, Virginia, MD
Smylie, Michael, MD
Schadendorf, Dirk, Prof
Mortier, Laurent, Prof
Svane, Inge Marie, MD
Hennicken, Delphine, MSc
Qureshi, Anila, MD
Maio, Michele, MD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_hal_primary_oai_HAL_inserm_01807340v1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_inserm_01807340v1
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(17)30231-0
