Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs durin...
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Sumolyation regulates wide-ranging biological processes, but its influence on innate immunity is unclear. Amigorena and colleagues show that sumoylation negatively regulates interferon-β expression and anti-viral immunity.
Innate sensing of pathogens initiates inflammatory cytokine responses that need to be tightly controlled. We found here that...
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Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
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TN_cdi_hal_primary_oai_HAL_pasteur_01380657v1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_hal_primary_oai_HAL_pasteur_01380657v1
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3342