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ArticlesPeer ReviewedFull Text
Transmission of innate immune signaling by packaging of cGAMP in viral particles
Author / Creator:Gentili, Matteo ; Kowal, Joanna ; Tkach, Mercedes ; Satoh, Takeshi ; Lahaye, Xavier ; Conrad, Cécile ; Boyron, Marilyn ; Lombard, Bérangère ; Durand, Sylvère ; Kroemer, Guido ; Loew, Damarys ; Dalod, Marc ; Théry, Clotilde ; Manel, Nicolas
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-09, Vol.349 (6253), p.1232-1236
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ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
Author / Creator:Raab, M. ; Gentili, M. ; de Belly, H. ; Thiam, H. R. ; Vargas, P. ; Jimenez, A. J. ; Lautenschlaeger, F. ; Voituriez, Raphaël ; Lennon-Duménil, A. M. ; Manel, N. ; Piel, M.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6283), p.359-362
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A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
Author / Creator:Manel, Nicolas ; Hogstad, Brandon ; Wang, Yaming ; Levy, David E. ; Unutmaz, Derya ; Littman, Dan R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2010-09, Vol.467 (7312), p.214-217
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A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway
Author / Creator:Zablocki-Thomas, Laurent ; Menzies, Sam A ; Lehner, Paul J ; Manel, Nicolas ; Benaroch, Philippe
Publisher:London, England: SAGE Publications
Journal title:Innate immunity (London, England), 2020-08, Vol.26 (6), p.459-472
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Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
Author / Creator:Eichholz, Karsten ; Bru, Thierry ; Tran, Thi Thu Phuong ; Fernandes, Paulo ; Welles, Hugh ; Mennechet, Franck J D ; Manel, Nicolas ; Alves, Paula ; Perreau, Matthieu ; Kremer, Eric J
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-09, Vol.12 (9), p.e1005871-e1005871
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Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
Author / Creator:Chauvin, Samuel D. ; Ando, Shoichiro ; Holley, Joe A. ; Sugie, Atsushi ; Zhao, Fang R. ; Poddar, Subhajit ; Kato, Rei ; Miner, Cathrine A. ; Nitta, Yohei ; Krishnamurthy, Siddharth R. ; Saito, Rie ; Ning, Yue ; Hatano, Yuya ; Kitahara, Sho ; Koide, Shin ; Stinson, W. Alexander ; Fu, Jiayuan ; Surve, Nehalee ; Kumble, Lindsay ; Qian, Wei ; Polishchuk, Oleksiy ; Andhey, Prabhakar S. ; Chiang, Cindy ; Liu, Guanqun ; Colombeau, Ludovic ; Rodriguez, Raphaël ; Manel, Nicolas ; Kakita, Akiyoshi ; Artyomov, Maxim N. ; Schultz, David C. ; Coates, P. Toby ; Roberson, Elisha D. O. ; Belkaid, Yasmine ; Greenberg, Roger A. ; Cherry, Sara ; Gack, Michaela U. ; Hardy, Tristan ; Onodera, Osamu ; Kato, Taisuke ; Miner, Jonathan J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.4696-23, Article 4696
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Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection
Author / Creator:Srivastava, Smita ; Swanson, Selene K ; Manel, Nicolas ; Florens, Laurence ; Washburn, Michael P ; Skowronski, Jacek
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2008-05, Vol.4 (5), p.e1000059
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HTLV-1 tropism and envelope receptor
Author / Creator:Manel, Nicolas ; Battini, Jean-Luc ; Taylor, Naomi ; Sitbon, Marc
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2005-09, Vol.24 (39), p.6016-6025
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Discovery of a druggable copper-signaling pathway that drives cell plasticity and inflammation
Author / Creator:Solier, Stephanie ; Muller, Sebastian ; Caneque, Tatiana ; Versini, Antoine ; Baron, Leeroy ; Gestraud, Pierre ; Servant, Nicolas ; Emam, Laila ; Mansart, Arnaud ; Pantos, G Dan ; Gandon, Vincent ; Sencio, Valentin ; Robin, Cyril ; Trottein, Francois ; Begue, Anne-Laure ; Salmon, Helene ; Durand, Sylvere ; Ting-Di, Wu ; Nicolas Manel ; Puisieux, Alain ; Dawson, Mark A ; Watson, Sarah ; Kroemer, Guido ; Annane, Djillali ; Rodriguez, Raphael
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:Nature (London), 2022-03, Vol.617, p.386-394
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Glucose Transporter 1 Expression Identifies a Population of Cycling CD4+CD8+Human Thymocytes with High CXCR4-Induced Chemotaxis
Author / Creator:Swainson, Louise ; Kinet, Sandrina ; Manel, Nicolas ; Battini, Jean-Luc ; Sitbon, Marc ; Taylor, Naomi ; Herzenberg, Leonard A.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (36), p.12867-12872
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Aicardi–Goutières syndrome and the type I interferonopathies
Author / Creator:Crow, Yanick J. ; Manel, Nicolas
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2015-07, Vol.15 (7), p.429-440
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Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells
Author / Creator:Kinet, Sandrina ; Swainson, Louise ; Lavanya, Madakasira ; Mongellaz, Cedric ; Montel-Hagen, Amélie ; Craveiro, Marco ; Manel, Nicolas ; Battini, Jean-Luc ; Sitbon, Marc ; Taylor, Naomi
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2007-05, Vol.4 (1), p.31-31, Article 31
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The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Author / Creator:Manel, Nicolas ; Unutmaz, Derya ; Littman, Dan R
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2008-06, Vol.9 (6), p.641-649
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Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations
Author / Creator:Jeremiah, Nadia ; Neven, Bénédicte ; Gentili, Matteo ; Callebaut, Isabelle ; Maschalidi, Sophia ; Stolzenberg, Marie-Claude ; Goudin, Nicolas ; Frémond, Marie-Louis ; Nitschke, Patrick ; Molina, Thierry J ; Blanche, Stéphane ; Picard, Capucine ; Rice, Gillian I ; Crow, Yanick J ; Manel, Nicolas ; Fischer, Alain ; Bader-Meunier, Brigitte ; Rieux-Laucat, Frédéric
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-12, Vol.124 (12), p.5516-5520
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Capture in the metabolic arena: co-selection of gamma and deltaretrovirus envelope glycoproteins and their receptors
Author / Creator:Sitbon, Marc ; Abe, Hiroyuki ; Courgnaud, Valerie ; Giovannini, Donatella ; Kim, Felix ; Lavanya, Madakasira ; Manel, Nicolas ; Touhami, Jawida ; Switzer, Wiliam M ; Castelnau, Pierre ; Lagrue, Emmanuelle ; Nadal-Desbarats, Lydie ; de Guillen, Karine ; Roumestand, Christian ; Battini, Jean-Luc
Publisher:London: BioMed Central
Journal title:Retrovirology, 2009-09, Vol.6 (Suppl 2), p.I20-I20, Article I20
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A druggable copper-signalling pathway that drives inflammation
Author / Creator:Solier, Stéphanie ; Müller, Sebastian ; Cañeque, Tatiana ; Versini, Antoine ; Mansart, Arnaud ; Sindikubwabo, Fabien ; Baron, Leeroy ; Emam, Laila ; Gestraud, Pierre ; Pantoș, G. Dan ; Gandon, Vincent ; Gaillet, Christine ; Wu, Ting-Di ; Dingli, Florent ; Loew, Damarys ; Baulande, Sylvain ; Durand, Sylvère ; Sencio, Valentin ; Robil, Cyril ; Trottein, François ; Péricat, David ; Näser, Emmanuelle ; Cougoule, Céline ; Meunier, Etienne ; Bègue, Anne-Laure ; Salmon, Hélène ; Manel, Nicolas ; Puisieux, Alain ; Watson, Sarah ; Dawson, Mark A. ; Servant, Nicolas ; Kroemer, Guido ; Annane, Djillali ; Rodriguez, Raphaël
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2023-05, Vol.617 (7960), p.386-394
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Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
Author / Creator:Decque, Adrien ; Joffre, Olivier ; Magalhaes, Joao G ; Cossec, Jack-Christophe ; Blecher-Gonen, Ronnie ; Lapaquette, Pierre ; Silvin, Aymeric ; Manel, Nicolas ; Joubert, Pierre-Emmanuel ; Seeler, Jacob-Sebastian ; Albert, Matthew L ; Amit, Ido ; Amigorena, Sebastian ; Dejean, Anne
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2016-02, Vol.17 (2), p.140-149
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Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection
Author / Creator:El Hed, Aimee ; Khaitan, Alka ; Kozhaya, Lina ; Manel, Nicolas ; Daskalakis, Demetre ; Borkowsky, William ; Valentine, Fred ; Littman, Dan R. ; Unutmaz, Derya
Publisher:United States: The University of Chicago Press
Journal title:The Journal of infectious diseases, 2010-03, Vol.201 (6), p.843-854
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Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
Author / Creator:Bhargava, Anvita ; Maurin, Mathieu ; Davidson, Patricia M ; Jouve, Mabel ; Lahaye, Xavier ; Nicolas Manel
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-12
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Combinatorial flexibility of cytokine function during human T helper cell differentiation
Author / Creator:Touzot, Maxime ; Grandclaudon, Maximilien ; Cappuccio, Antonio ; Satoh, Takeshi ; Martinez-Cingolani, Carolina ; Servant, Nicolas ; Manel, Nicolas ; Soumelis, Vassili
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-05, Vol.5 (1), p.3987-3987, Article 3987
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Transmission of innate immune signaling by packaging of cGAMP in viral particles

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ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

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A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

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A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway

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Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

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Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans

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Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

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HTLV-1 tropism and envelope receptor

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Discovery of a druggable copper-signaling pathway that drives cell plasticity and inflammation

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Glucose Transporter 1 Expression Identifies a Population of Cycling CD4+CD8+Human Thymocytes with High CXCR4-Induced Chemotaxis

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Aicardi–Goutières syndrome and the type I interferonopathies

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Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells

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The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

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Inherited STING-activating mutation underlies a familial inflammatory syndrome with lupus-like manifestations

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Capture in the metabolic arena: co-selection of gamma and deltaretrovirus envelope glycoproteins and their receptors

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A druggable copper-signalling pathway that drives inflammation

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Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

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Susceptibility of Human Th17 Cells to Human Immunodeficiency Virus and Their Perturbation during Infection

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Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics

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Combinatorial flexibility of cytokine function during human T helper cell differentiation

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