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Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ gr...

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ gr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25756870

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

About this item

Full title

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21248-21255

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Priming of the organ-specific premetastatic sites is thought to be an important yet incompletely understood step during metastasis. In this study, we show that the metastatic tumors we examined overexpress granulocyte-colony stimulating factor (G-CSF), which expands and mobilizes Ly6G+Ly6C+ granulocytes and facilitates their subsequent homing at di...

Alternative Titles

Full title

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_jstor_primary_25756870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_25756870

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1015855107

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