STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Spontaneous CD8 T-cell responses occur in growing tumors but are usually poorly effective. Understanding the molecular and cellular mechanisms that drive these responses is of major interest as they could be exploited to generate a more efficacious antitumor immunity. As such, stimulator of IFN genes (STING), an adaptor molecule involved in cytosol...
Alternative Titles
Full title
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
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TN_cdi_jstor_primary_26466609
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_jstor_primary_26466609
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1512832112
