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ArticlesPeer ReviewedFull Text
Psoriasis: from Pathogenesis to Targeted Therapies
Author / Creator:Conrad, Curdin ; Gilliet, Michel
Publisher:New York: Springer US
Journal title:Clinical reviews in allergy & immunology, 2018-02, Vol.54 (1), p.102-113
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The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
Author / Creator:Di Domizio, Jeremy ; Belkhodja, Cyrine ; Chenuet, Pauline ; Fries, Anissa ; Murray, Timothy ; Mondéjar, Paula Marcos ; Demaria, Olivier ; Conrad, Curdin ; Homey, Bernhard ; Werner, Sabine ; Speiser, Daniel E. ; Ryffel, Bernhard ; Gilliet, Michel
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2020-09, Vol.21 (9), p.1034-1045
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The cGAS–STING pathway drives type I IFN immunopathology in COVID-19
Author / Creator:Domizio, Jeremy Di ; Gulen, Muhammet F. ; Saidoune, Fanny ; Thacker, Vivek V. ; Yatim, Ahmad ; Sharma, Kunal ; Nass, Théo ; Guenova, Emmanuella ; Schaller, Martin ; Conrad, Curdin ; Goepfert, Christine ; de Leval, Laurence ; Garnier, Christophe von ; Berezowska, Sabina ; Dubois, Anaëlle ; Gilliet, Michel ; Ablasser, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-03, Vol.603 (7899), p.145-151
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Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9
Author / Creator:Lee, Ernest Y. ; Zhang, Changsheng ; Di Domizio, Jeremy ; Jin, Fan ; Connell, Will ; Hung, Mandy ; Malkoff, Nicolas ; Veksler, Veronica ; Gilliet, Michel ; Ren, Pengyu ; Wong, Gerard C. L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-03, Vol.10 (1), p.1012-1012, Article 1012
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TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis
Author / Creator:Conrad, Curdin ; Di Domizio, Jeremy ; Mylonas, Alessio ; Belkhodja, Cyrine ; Demaria, Olivier ; Navarini, Alexander A. ; Lapointe, Anne-Karine ; French, Lars E. ; Vernez, Maxime ; Gilliet, Michel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-01, Vol.9 (1), p.25-25, Article 25
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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
Author / Creator:Demaria, Olivier ; De Gassart, Aude ; Coso, Sanja ; Gestermann, Nicolas ; Di Domizio, Jeremy ; Flatz, Lukas ; Gaide, Olivier ; Michielin, Olivier ; Hwu, Patrick ; Petrova, Tatiana V. ; Martinon, Fabio ; Modlin, Robert L. ; Speiser, Daniel E. ; Gilliet, Michel
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.15408-15413
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Integrated multi-omics reveals cellular and molecular interactions governing the invasive niche of basal cell carcinoma
Author / Creator:Yerly, Laura ; Pich-Bavastro, Christine ; Di Domizio, Jeremy ; Wyss, Tania ; Tissot-Renaud, Stéphanie ; Cangkrama, Michael ; Gilliet, Michel ; Werner, Sabine ; Kuonen, François
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4897-4897, Article 4897
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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
Author / Creator:Ma, Feiyang ; Plazyo, Olesya ; Billi, Allison C. ; Tsoi, Lam C. ; Xing, Xianying ; Wasikowski, Rachael ; Gharaee-Kermani, Mehrnaz ; Hile, Grace ; Jiang, Yanyun ; Harms, Paul W. ; Xing, Enze ; Kirma, Joseph ; Xi, Jingyue ; Hsu, Jer-En ; Sarkar, Mrinal K. ; Chung, Yutein ; Di Domizio, Jeremy ; Gilliet, Michel ; Ward, Nicole L. ; Maverakis, Emanual ; Klechevsky, Eynav ; Voorhees, John J. ; Elder, James T. ; Lee, Jun Hee ; Kahlenberg, J. Michelle ; Pellegrini, Matteo ; Modlin, Robert L. ; Gudjonsson, Johann E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-06, Vol.14 (1), p.3455-19, Article 3455
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TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26
Author / Creator:Meller, Stephan ; Di Domizio, Jeremy ; Voo, Kui S ; Friedrich, Heike C ; Chamilos, Georgios ; Ganguly, Dipyaman ; Conrad, Curdin ; Gregorio, Josh ; Le Roy, Didier ; Roger, Thierry ; Ladbury, John E ; Homey, Bernhard ; Watowich, Stanley ; Modlin, Robert L ; Kontoyiannis, Dimitrios P ; Liu, Yong-Jun ; Arold, Stefan T ; Gilliet, Michel
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-09, Vol.16 (9), p.970-979
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ArticlesPeer ReviewedFull Text
Diversification of human plasmacytoid predendritic cells in response to a single stimulus
Author / Creator:Alculumbre, Solana G. ; Saint-André, Violaine ; Di Domizio, Jeremy ; Vargas, Pablo ; Sirven, Philemon ; Bost, Pierre ; Maurin, Mathieu ; Maiuri, Paolo ; Wery, Maxime ; Roman, Mabel San ; Savey, Léa ; Touzot, Maxime ; Terrier, Benjamin ; Saadoun, David ; Conrad, Curdin ; Gilliet, Michel ; Morillon, Antonin ; Soumelis, Vassili
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2018-01, Vol.19 (1), p.63-75
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Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis
Author / Creator:Fries, Anissa ; Saidoune, Fanny ; Kuonen, François ; Dupanloup, Isabelle ; Fournier, Nadine ; Guerra de Souza, Ana Cristina ; Haniffa, Muzlifah ; Ma, Feiyang ; Gudjonsson, Johann E. ; Roesner, Lennart ; Li, Yang ; Werfel, Thomas ; Conrad, Curdin ; Gottardo, Raphael ; Modlin, Robert L. ; Di Domizio, Jeremy ; Gilliet, Michel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-06, Vol.14 (1), p.3878-3878, Article 3878
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IL-26 contributes to host defense against intracellular bacteria
Author / Creator:Dang, Angeline Tilly ; Teles, Rosane Mb ; Weiss, David I ; Parvatiyar, Kislay ; Sarno, Euzenir N ; Ochoa, Maria T ; Cheng, Genhong ; Gilliet, Michel ; Bloom, Barry R ; Modlin, Robert L
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2019-05, Vol.129 (5), p.1926-1939
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Liquid-crystalline ordering of antimicrobial peptide–DNA complexes controls TLR9 activation
Author / Creator:Schmidt, Nathan W. ; Jin, Fan ; Lande, Roberto ; Curk, Tine ; Xian, Wujing ; Lee, Calvin ; Frasca, Loredana ; Frenkel, Daan ; Dobnikar, Jure ; Gilliet, Michel ; Wong, Gerard C. L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature materials, 2015-07, Vol.14 (7), p.696-700
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ArticlesPeer ReviewedFull Text
Immune modules to guide diagnosis and personalized treatment of inflammatory skin diseases
Author / Creator:Seremet, Teofila ; Di Domizio, Jeremy ; Girardin, Antoine ; Yatim, Ahmad ; Jenelten, Raphael ; Messina, Francesco ; Saidoune, Fanny ; Schlapbach, Christoph ; Bogiatzi, Sofia ; Minisini, Frederic ; Garzorz-Stark, Natalie ; Leuenberger, Matthieu ; Wüthrich, Héloise ; Vernez, Maxime ; Hohl, Daniel ; Eyerich, Stefanie ; Eyerich, Kilian ; Guenova, Emmanuella ; Paul, Carle ; Gottardo, Raphael ; Conrad, Curdin ; Gilliet, Michel
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-12, Vol.15 (1), p.10688-12, Article 10688
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Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation
Author / Creator:Zwicker, Stephanie ; Hattinger, Eva ; Bureik, Daniela ; Batycka-Baran, Aleksandra ; Schmidt, Andreas ; Gerber, Peter-Arne ; Rothenfusser, Simon ; Gilliet, Michel ; Ruzicka, Thomas ; Wolf, Ronald
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017, Vol.12 (4), p.e0175153-e0175153
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Generation of IL-23 Producing Dendritic Cells (DCs) by Airborne Fungi Regulates Fungal Pathogenicity via the Induction of TH-17 Responses
Author / Creator:Chamilos, Georgios ; Ganguly, Dipyaman ; Lande, Roberto ; Gregorio, Josh ; Meller, Stephan ; Goldman, William E. ; Gilliet, Michel ; Kontoyiannis, Dimitrios P.
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2010-09, Vol.5 (9), p.e12955
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Drosophila Melanogaster as a Model Host to Dissect the Immunopathogenesis of Zygomycosis
Author / Creator:Chamilos, Georgios ; Lewis, Russell E. ; Hu, Jianhua ; Xiao, Lianchun ; Zal, Tomasz ; Gilliet, Michel ; Halder, Georg ; Kontoyiannis, Dimitrios P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (27), p.9367-9372
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ArticlesPeer ReviewedFull Text
OX40 Ligand Shuts down IL-10-Producing Regulatory T Cells
Author / Creator:Ito, Tomoki ; Wang, Yui-Hsi ; Duramad, Omar ; Hanabuchi, Shino ; Perng, Olivia A. ; Gilliet, Michel ; Qin, F. Xiao-Feng ; Liu, Yong-Jun
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (35), p.13138-13143
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ArticlesPeer ReviewedFull Text
Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity
Author / Creator:Di Domizio, Jeremy ; Dorta-Estremera, Stephanie ; Gagea, Mihai ; Ganguly, Dipyaman ; Meller, Stephan ; Li, Ping ; Zhao, Bihong ; Tan, Filemon K ; Bi, Liqi ; Gilliet, Michel ; Cao, Wei
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (36), p.14550-14555
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Generation of Monoclonal Antibodies Specific for Native LL37 and Citrullinated LL37 That Discriminate the Two LL37 Forms in the Skin and Circulation of Cutaneous/Systemic Lupus Erythematosus and Rheum...
Author / Creator:Lande, Roberto ; Palazzo, Raffaella ; Hammel, Philippe ; Pietraforte, Immacolata ; Surbeck, Isabelle ; Gilliet, Michel ; Chizzolini, Carlo ; Frasca, Loredana
Publisher:Switzerland: MDPI
Journal title:Antibodies (Basel), 2020-05, Vol.9 (2), p.14
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Psoriasis: from Pathogenesis to Targeted Therapies

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The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin

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The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

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Helical antimicrobial peptides assemble into protofibril scaffolds that present ordered dsDNA to TLR9

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TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis

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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

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Integrated multi-omics reveals cellular and molecular interactions governing the invasive niche of basal cell carcinoma

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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis

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TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

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Diversification of human plasmacytoid predendritic cells in response to a single stimulus

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Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis

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IL-26 contributes to host defense against intracellular bacteria

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Liquid-crystalline ordering of antimicrobial peptide–DNA complexes controls TLR9 activation

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Immune modules to guide diagnosis and personalized treatment of inflammatory skin diseases

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Th17 micro-milieu regulates NLRP1-dependent caspase-5 activity in skin autoinflammation

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Generation of IL-23 Producing Dendritic Cells (DCs) by Airborne Fungi Regulates Fungal Pathogenicity via the Induction of TH-17 Responses

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Drosophila Melanogaster as a Model Host to Dissect the Immunopathogenesis of Zygomycosis

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OX40 Ligand Shuts down IL-10-Producing Regulatory T Cells

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Nucleic acid-containing amyloid fibrils potently induce type I interferon and stimulate systemic autoimmunity

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Generation of Monoclonal Antibodies Specific for Native LL37 and Citrullinated LL37 That Discriminate the Two LL37 Forms in the Skin and Circulation of Cutaneous/Systemic Lupus Erythematosus and Rheum...

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