Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion...
Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Prion diseases are fatal neurodegenerative diseases, which can be acquired, sporadic or genetic, the latter being linked to mutations in the gene encoding prion protein. We have recently described the importance of subdomain separation in the conversion of prion protein (PrP). The goal of the present study was to investigate the effect of increasin...
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Effect of Hydrophobic Mutations in the H2-H3 Subdomain of Prion Protein on Stability and Conversion In Vitro and In Vivo
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TN_cdi_plos_journals_1308603745
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1308603745
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0024238
