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Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine recepto...

Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine recepto...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327136667

Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine receptor-STAT3 pathway

About this item

Full title

Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine receptor-STAT3 pathway

Publisher

United States: Public Library of Science

Journal title

PloS one, 2012-12, Vol.7 (12), p.e51217-e51217

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

This study was to investigate the effect of nicotine on insulin sensitivity and explore the underlying mechanisms. Treatment of Sprague-Dawley rats with nicotine (3 mg/kg/day) for 6 weeks reduced 43% body weight gain and 65% blood insulin level, but had no effect on blood glucose level. Both insulin tolerance test and glucose tolerance test demonst...

Alternative Titles

Full title

Chronic exposure to nicotine enhances insulin sensitivity through α7 nicotinic acetylcholine receptor-STAT3 pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1327136667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1327136667

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0051217

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