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Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1

Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330893567

Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1

About this item

Full title

Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-04, Vol.8 (4), p.e61166

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved domain (LLRKxGxKG) of MHV nsp1, a mutant virus, MHV-n...

Alternative Titles

Full title

Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1330893567

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1330893567

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0061166

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