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Silencing of reversion-inducing cysteine-rich protein with Kazal motifs stimulates hyperplastic phen...

Silencing of reversion-inducing cysteine-rich protein with Kazal motifs stimulates hyperplastic phen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1470083188

Silencing of reversion-inducing cysteine-rich protein with Kazal motifs stimulates hyperplastic phenotypes through activation of epidermal growth factor receptor and hypoxia-inducible factor-2α

About this item

Full title

Silencing of reversion-inducing cysteine-rich protein with Kazal motifs stimulates hyperplastic phenotypes through activation of epidermal growth factor receptor and hypoxia-inducible factor-2α

Publisher

United States: Public Library of Science

Journal title

PloS one, 2013-12, Vol.8 (12), p.e84520

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Reversion-inducing cysteine-rich protein with Kazal motifs (RECK, a tumor suppressor) is down-regulated by the oncogenic signals and hypoxia, but the biological function of RECK in early tumorigenic hyperplastic phenotypes is largely unknown. Knockdown of RECK by small interfering RNA (siRECK) or hypoxia significantly promoted cell proliferation in...

Alternative Titles

Full title

Silencing of reversion-inducing cysteine-rich protein with Kazal motifs stimulates hyperplastic phenotypes through activation of epidermal growth factor receptor and hypoxia-inducible factor-2α

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1470083188

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1470083188

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0084520

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