Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants
Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants
About this item
Full title
Author / Creator
Rehker, Jan , Rodhe, Johanna , Nesbitt, Ryan R , Boyle, Evan A , Martin, Beth K , Lord, Jenny , Karaca, Ilker , Naj, Adam , Jessen, Frank , Helisalmi, Seppo , Soininen, Hilkka , Hiltunen, Mikko , Ramirez, Alfredo , Scherer, Martin , Farrer, Lindsay A , Haines, Jonathan L , Pericak-Vance, Margaret A , Raskind, Wendy H , Cruchaga, Carlos , Schellenberg, Gerard D , Joseph, Bertrand and Brkanac, Zoran
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The accumulation of amyloid beta (Aβ) peptide (Amyloid cascade hypothesis), an APP protein cleavage product, is a leading hypothesis in the etiology of Alzheimer's disease (AD). In order to identify additional AD risk genes, we performed targeted sequencing and rare variant burden association study for nine candidate genes involved in the amyloid m...
Alternative Titles
Full title
Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants
Authors, Artists and Contributors
Author / Creator
Rodhe, Johanna
Nesbitt, Ryan R
Boyle, Evan A
Martin, Beth K
Lord, Jenny
Karaca, Ilker
Naj, Adam
Jessen, Frank
Helisalmi, Seppo
Soininen, Hilkka
Hiltunen, Mikko
Ramirez, Alfredo
Scherer, Martin
Farrer, Lindsay A
Haines, Jonathan L
Pericak-Vance, Margaret A
Raskind, Wendy H
Cruchaga, Carlos
Schellenberg, Gerard D
Joseph, Bertrand
Brkanac, Zoran
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1947850745
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1947850745
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0185777
