Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic n...
Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice
About this item
Full title
Author / Creator
Koestner, Wolfgang , Spanier, Julia , Klause, Tanja , Tegtmeyer, Pia-K , Becker, Jennifer , Herder, Vanessa , Borst, Katharina , Todt, Daniel , Lienenklaus, Stefan , Gerhauser, Ingo , Detje, Claudia N , Geffers, Robert , Langereis, Martijn A , Vondran, Florian W R , Yuan, Qinggong , van Kuppeveld, Frank J M , Ott, Michael , Staeheli, Peter , Steinmann, Eike , Baumgärtner, Wolfgang , Wacker, Frank and Kalinke, Ulrich
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
During Coxsackievirus B3 (CVB3) infection hepatitis is a potentially life threatening complication, particularly in newborns. Studies with type I interferon (IFN-I) receptor (IFNAR)-deficient mice revealed a key role of the IFN-I axis in the protection against CVB3 infection, whereas the source of IFN-I and cell types that have to be IFNAR triggere...
Alternative Titles
Full title
Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice
Authors, Artists and Contributors
Author / Creator
Spanier, Julia
Klause, Tanja
Tegtmeyer, Pia-K
Becker, Jennifer
Herder, Vanessa
Borst, Katharina
Todt, Daniel
Lienenklaus, Stefan
Gerhauser, Ingo
Detje, Claudia N
Geffers, Robert
Langereis, Martijn A
Vondran, Florian W R
Yuan, Qinggong
van Kuppeveld, Frank J M
Ott, Michael
Staeheli, Peter
Steinmann, Eike
Baumgärtner, Wolfgang
Wacker, Frank
Kalinke, Ulrich
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2251085085
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2251085085
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1007235
