Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of de...
Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The adhesion G-protein coupled receptor Adgrg6 (formerly Gpr126) is instrumental in the development, maintenance and repair of peripheral nervous system myelin. The prion protein (PrP) is a potent activator of Adgrg6 and could be used as a potential therapeutic agent in treating peripheral demyelinating and dysmyelinating diseases. We designed a di...
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Soluble dimeric prion protein ligand activates Adgrg6 receptor but does not rescue early signs of demyelination in PrP-deficient mice
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TN_cdi_plos_journals_2460089919
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2460089919
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0242137
