Efficient and flexible Integration of variant characteristics in rare variant association studies us...
Efficient and flexible Integration of variant characteristics in rare variant association studies using integrated nested Laplace approximation
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Rare variants are thought to play an important role in the etiology of complex diseases and may explain a significant fraction of the missing heritability in genetic disease studies. Next-generation sequencing facilitates the association of rare variants in coding or regulatory regions with complex diseases in large cohorts at genome-wide scale. Ho...
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Full title
Efficient and flexible Integration of variant characteristics in rare variant association studies using integrated nested Laplace approximation
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TN_cdi_plos_journals_2501880263
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2501880263
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ISSN
1553-7358,1553-734X
E-ISSN
1553-7358
DOI
10.1371/journal.pcbi.1007784
