Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state
Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
In contrast to mammals, lower vertebrates are capable of extraordinary myocardial regeneration thanks to the ability of their cardiomyocytes to undergo transient dedifferentiation and proliferation. Somatic cells can be temporarily reprogrammed to a proliferative, dedifferentiated state through forced expression of Oct3/4, Sox2, Klf4 and c-Myc (OSK...
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Full title
Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state
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TN_cdi_plos_journals_2522383682
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2522383682
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0251054
