Phosphatidylserine receptors enhance SARS-CoV-2 infection
Phosphatidylserine receptors enhance SARS-CoV-2 infection
About this item
Full title
Author / Creator
Bohan, Dana , Van Ert, Hanora , Ruggio, Natalie , Rogers, Kai J , Badreddine, Mohammad , Aguilar Briseño, José A , Elliff, Jonah M , Rojas Chavez, Roberth Anthony , Gao, Boning , Stokowy, Tomasz , Christakou, Eleni , Kursula, Petri , Micklem, David , Gausdal, Gro , Haim, Hillel , Minna, John , Lorens, James B and Maury, Wendy
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Phosphatidylserine (PS) receptors enhance infection of many enveloped viruses through virion-associated PS binding that is termed apoptotic mimicry. Here we show that this broadly shared uptake mechanism is utilized by SARS-CoV-2 in cells that express low surface levels of ACE2. Expression of members of the TIM (TIM-1 and TIM-4) and TAM (AXL) famil...
Alternative Titles
Full title
Phosphatidylserine receptors enhance SARS-CoV-2 infection
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2610940208
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2610940208
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1009743
