The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pedi...
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma
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Author / Creator
Bočkaj, Irena , Martini, Tosca E I , de Camargo Magalhães, Eduardo S , Bakker, Petra L , Meeuwsen-de Boer, Tiny G J , Armandari, Inna , Meuleman, Saskia L , Mondria, Marin T , Stok, Colin , Kok, Yannick P , Bakker, Bjorn , Wardenaar, René , Seiler, Jonas , Broekhuis, Mathilde J C , van den Bos, Hilda , Spierings, Diana C J , Ringnalda, Femke C A , Clevers, Hans , Schüller, Ulrich , van Vugt, Marcel A T M , Foijer, Floris and Bruggeman, Sophia W M
Publisher
United States: Public Library of Science
Journal title
Language
English
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Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
While comprehensive molecular profiling of histone H3.3 mutant pediatric high-grade glioma has revealed extensive dysregulation of the chromatin landscape, the exact mechanisms driving tumor formation remain poorly understood. Since H3.3 mutant gliomas also exhibit high levels of copy number alterations, we set out to address if the H3.3K27M oncohi...
Alternative Titles
Full title
The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma
Authors, Artists and Contributors
Author / Creator
Martini, Tosca E I
de Camargo Magalhães, Eduardo S
Bakker, Petra L
Meeuwsen-de Boer, Tiny G J
Armandari, Inna
Meuleman, Saskia L
Mondria, Marin T
Stok, Colin
Kok, Yannick P
Bakker, Bjorn
Wardenaar, René
Seiler, Jonas
Broekhuis, Mathilde J C
van den Bos, Hilda
Spierings, Diana C J
Ringnalda, Femke C A
Clevers, Hans
Schüller, Ulrich
van Vugt, Marcel A T M
Foijer, Floris
Bruggeman, Sophia W M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_2610943806
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2610943806
Other Identifiers
ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1009868
