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Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2737135433

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

About this item

Full title

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

Publisher

San Francisco: Public Library of Science

Journal title

PLoS biology, 2022-10, Vol.20 (10), p.e3001813-e3001813

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

The reduced sleep duration previously observed in
Camk2b
knockout mice revealed a role for Ca
2+
/calmodulin-dependent protein kinase II (CaMKII)β as a sleep-promoting kinase. However, the underlying mechanism by which CaMKIIβ supports sleep regulation is largely unknown. Here, we demonstrate that activation or inhibition of CaMKIIβ can...

Alternative Titles

Full title

Distinct phosphorylation states of mammalian CaMKIIβ control the induction and maintenance of sleep

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_2737135433

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2737135433

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.3001813

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