Structural basis for amyloidogenic peptide recognition by sorLA
Structural basis for amyloidogenic peptide recognition by sorLA
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Publisher
New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The neuronal sorting receptor SorLA protects against Alzheimer's disease by binding Aβ peptides. Three new structures of the Vps10p Aβ-binding domain in ligand-free and ligand-bound forms explain the basis of SorLA peptide recognition.
SorLA is a neuronal sorting receptor considered to be a major risk factor for Alzheimer's disease. We have rece...
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Structural basis for amyloidogenic peptide recognition by sorLA
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TN_cdi_proquest_journals_1660689364
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1660689364
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2954
