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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1730676524

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

About this item

Full title

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2015-10, Vol.526 (7575), p.666-671

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Intracellular lipopolysaccharide from Gram-negative bacteria including
Escherichia coli
,
Salmonella typhimurium
,
Shigella flexneri
, and
Burkholderia thailandensis
activates mouse caspase-11, causing pyroptotic cell death, interleukin-1β processing, and lethal septic shock. How caspase-11 executes these downstream signalli...

Alternative Titles

Full title

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_1730676524

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_1730676524

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature15541

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