Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a mult...
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
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for the BG-12 Phase IIb Study Investigators , BG-12 Phase IIb Study Investigators , Kappos, Ludwig, Prof , Gold, Ralf, Prof , Miller, David H, Prof , MacManus, David G, MSc , Havrdova, Eva, MD , Limmroth, Volker, MD , Polman, Chris H, Prof , Schmierer, Klaus, PhD , Yousry, Tarek A, MD , Yang, Minhua, MS , Eraksoy, Mefkûre, Prof , Meluzinova, Eva, MD , Rektor, Ivan, MD , Dawson, Katherine T, MD , Sandrock, Alfred W, MD and O'Neill, Gilmore N, MB
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background Oral fumarate (BG00012) might have dual anti-inflammatory and neuroprotective effects. Our aim was to assess the efficacy and safety of BG00012 in patients with relapsing-remitting multiple sclerosis. Methods 257 patients, aged 18–55 years, with relapsing-remitting multiple sclerosis were randomly assigned to receive 120 mg once...
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Full title
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Authors, Artists and Contributors
Author / Creator
BG-12 Phase IIb Study Investigators
Kappos, Ludwig, Prof
Gold, Ralf, Prof
Miller, David H, Prof
MacManus, David G, MSc
Havrdova, Eva, MD
Limmroth, Volker, MD
Polman, Chris H, Prof
Schmierer, Klaus, PhD
Yousry, Tarek A, MD
Yang, Minhua, MS
Eraksoy, Mefkûre, Prof
Meluzinova, Eva, MD
Rektor, Ivan, MD
Dawson, Katherine T, MD
Sandrock, Alfred W, MD
O'Neill, Gilmore N, MB
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Record Identifier
TN_cdi_proquest_journals_199032388
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_199032388
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(08)61619-0
