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ArticlesPeer ReviewedFull Text
Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial
Author / Creator:Calabresi, Peter A, Dr ; Radue, Ernst-Wilhelm, Prof ; Goodin, Douglas, MD ; Jeffery, Douglas, MD ; Rammohan, Kottil W, MD ; Reder, Anthony T, MD ; Vollmer, Timothy, MD ; Agius, Mark A, MD ; Kappos, Ludwig, Prof ; Stites, Tracy, PhD ; Li, Bingbing, PhD ; Cappiello, Linda, MD ; von Rosenstiel, Philipp, MD ; Lublin, Fred D, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2014-06, Vol.13 (6), p.545-556
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ArticlesPeer ReviewedFull Text
Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial
Author / Creator:Confavreux, Christian, Prof ; O'Connor, Paul, Prof ; Comi, Giancarlo, Prof ; Freedman, Mark S, Prof ; Miller, Aaron E, Prof ; Olsson, Tomas P, Prof ; Wolinsky, Jerry S, Prof ; Bagulho, Teresa, MD ; Delhay, Jean-Luc, MD ; Dukovic, Deborah, MS ; Truffinet, Philippe, MD ; Kappos, Ludwig, Prof
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2014-03, Vol.13 (3), p.247-256
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ArticlesPeer ReviewedFull Text
Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial
Author / Creator:Lublin, Fred, Prof ; Miller, David H, Prof ; Freedman, Mark S, Prof ; Cree, Bruce A C, Prof ; Wolinsky, Jerry S, Prof ; Weiner, Howard, Prof ; Lubetzki, Catherine, Prof ; Hartung, Hans-Peter, Prof ; Montalban, Xavier, Prof ; Uitdehaag, Bernard M J, Prof ; Merschhemke, Martin, MD ; Li, Bingbing, PhD ; Putzki, Norman, MD ; Liu, Fonda C, PharmD ; Häring, Dieter A, PhD ; Kappos, Ludwig, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-03, Vol.387 (10023), p.1075-1084
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ArticlesPeer ReviewedFull Text
Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial
Author / Creator:Kappos, Ludwig, Prof ; Hartung, Hans-Peter, Prof ; Freedman, Mark S, Prof ; Boyko, Alexey, Prof ; Radü, Ernst Wilhelm, Prof ; Mikol, Daniel D, MD ; Lamarine, Marc, PhD ; Hyvert, Yann, PhD ; Freudensprung, Ulrich, MS ; Plitz, Thomas, PhD ; van Beek, Johan, PhD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2014-04, Vol.13 (4), p.353-363
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ArticlesPeer ReviewedFull Text
Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial
Author / Creator:Kappos, Ludwig, Prof ; Li, David, MD ; Calabresi, Peter A, MD ; O'Connor, Paul, MD ; Bar-Or, Amit, MD ; Barkhof, Frederik, Prof ; Yin, Ming, PhD ; Leppert, David, MD ; Glanzman, Robert, MD ; Tinbergen, Jeroen, MD ; Hauser, Stephen L, Prof
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2011-11, Vol.378 (9805), p.1779-1787
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ArticlesPeer ReviewedFull Text
Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study
Author / Creator:Selmaj, Krzysztof, Prof ; Li, David KB, Prof ; Hartung, Hans-Peter, Prof ; Hemmer, Bernhard, Prof ; Kappos, Ludwig, Prof ; Freedman, Mark S, Prof ; Stüve, Olaf, MD ; Rieckmann, Peter, Prof ; Montalban, Xavier, Prof ; Ziemssen, Tjalf, MD ; Auberson, Lixin Zhang, MD ; Pohlmann, Harald, MSc ; Mercier, Francois, PhD ; Dahlke, Frank, MD ; Wallström, Erik, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2013-08, Vol.12 (8), p.756-767
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ArticlesPeer ReviewedFull Text
Comparison of two dosing frequencies of subcutaneous interferon beta-1a in patients with a first clinical demyelinating event suggestive of multiple sclerosis (REFLEX): a phase 3 randomised controlled...
Author / Creator:Comi, Giancarlo, Prof ; De Stefano, Nicola, Prof ; Freedman, Mark S, Prof ; Barkhof, Frederik, Prof ; Polman, Chris H, Prof ; Uitdehaag, Bernard MJ, Prof ; Casset-Semanaz, Florence, MSc ; Hennessy, Brian, MSc ; Moraga, Margaretha Stam, MSc ; Rocak, Sanda, PhD ; Stubinski, Bettina, MD ; Kappos, Ludwig, Prof
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2012, Vol.11 (1), p.33-41
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ArticlesPeer ReviewedFull Text
Safety and efficacy of amiselimod in relapsing multiple sclerosis (MOMENTUM): a randomised, double-blind, placebo-controlled phase 2 trial
Author / Creator:Kappos, Ludwig, Prof ; Arnold, Douglas L, Prof ; Bar-Or, Amit, Prof ; Camm, John, Prof ; Derfuss, Tobias, Prof ; Kieseier, Bernd C, Prof ; Sprenger, Till, Prof ; Greenough, Kristin, MSc ; Ni, Pingping, PhD ; Harada, Tomohiko, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2016-10, Vol.15 (11), p.1148-1159
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ArticlesPeer ReviewedFull Text
Relapse and disability outcomes in patients with multiple sclerosis treated with fingolimod: subgroup analyses of the double-blind, randomised, placebo-controlled FREEDOMS study
Author / Creator:Devonshire, Virginia, MD ; Havrdova, Eva, MD ; Radue, Ernst Wilhelm, Prof ; O'Connor, Paul, MD ; Zhang-Auberson, Lixin, MD ; Agoropoulou, Catherine, PhD ; Häring, Dieter Adrian, PhD ; Francis, Gordon, MD ; Kappos, Ludwig, Prof
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2012-05, Vol.11 (5), p.420-428
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ArticlesPeer ReviewedFull Text
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Author / Creator:Kappos, Ludwig, Prof ; Gold, Ralf, Prof ; Miller, David H, Prof ; MacManus, David G, MSc ; Havrdova, Eva, MD ; Limmroth, Volker, MD ; Polman, Chris H, Prof ; Schmierer, Klaus, PhD ; Yousry, Tarek A, MD ; Yang, Minhua, MS ; Eraksoy, Mefkûre, Prof ; Meluzinova, Eva, MD ; Rektor, Ivan, MD ; Dawson, Katherine T, MD ; Sandrock, Alfred W, MD ; O'Neill, Gilmore N, MB
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2008-10, Vol.372 (9648), p.1463-1472
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ArticlesPeer ReviewedFull Text
Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study
Author / Creator:Kappos, Ludwig, Prof ; Freedman, Mark S, Prof ; Polman, Chris H, Prof ; Edan, Gilles, Prof ; Hartung, Hans-Peter, Prof ; Miller, David H, Prof ; Montalbán, Xavier, Prof ; Barkhof, Frederik, Prof ; Radü, Ernst-Wilhelm, Prof ; Bauer, Lars, MD ; Dahms, Susanne, PhD ; Lanius, Vivian, PhD ; Pohl, Christoph, MD ; Sandbrink, Rupert, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2007-08, Vol.370 (9585), p.389-397
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ArticlesPeer ReviewedFull Text
Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring
Author / Creator:Kappos, Ludwig, Prof ; Bates, David, MD ; Hartung, Hans-Peter, MD ; Havrdova, Eva, MD ; Miller, David, MD ; Polman, Chris H, MD ; Ravnborg, Mads, MD ; Hauser, Stephen L, MD ; Rudick, Richard A, MD ; Weiner, Howard L, MD ; O'Connor, Paul W, MD ; King, John, MD ; Radue, Ernst Wilhelm, MD ; Yousry, Tarek, MD ; Major, Eugene O, PhD ; Clifford, David B, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2007-05, Vol.6 (5), p.431-441
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Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial

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Oral teriflunomide for patients with relapsing multiple sclerosis (TOWER): a randomised, double-blind, placebo-controlled, phase 3 trial

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Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial

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Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial

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Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial

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Siponimod for patients with relapsing-remitting multiple sclerosis (BOLD): an adaptive, dose-ranging, randomised, phase 2 study

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Comparison of two dosing frequencies of subcutaneous interferon beta-1a in patients with a first clinical demyelinating event suggestive of multiple sclerosis (REFLEX): a phase 3 randomised controlled...

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Safety and efficacy of amiselimod in relapsing multiple sclerosis (MOMENTUM): a randomised, double-blind, placebo-controlled phase 2 trial

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Relapse and disability outcomes in patients with multiple sclerosis treated with fingolimod: subgroup analyses of the double-blind, randomised, placebo-controlled FREEDOMS study

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Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

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Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study

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Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring

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