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Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence

Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2310519676

Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence

About this item

Full title

Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2019-10

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Senescence is a phenotypic state of stable proliferative arrest, typically occurring in lineage-committed cells and triggered by various stimuli. It is generally accompanied by activation of a secretory program (senescence-associated secretory phenotype, SASP), which modulates both local (tissue microenvironment) and systemic (ageing) homeostasis....

Alternative Titles

Full title

Transcription-driven cohesin repositioning rewires chromatin loops in cellular senescence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2310519676

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2310519676

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/823831