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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2435015614

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) are thought to restrict numerous viral pathogens including severe acute respiratory syndrome coronaviruses (SARS-CoVs). However, most evidence comes from single-round pseudovirus infection studies of cells that overexpress IFITMs. Here, we verified that artificial overexpression of IFITM...

Alternative Titles

Full title

IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2435015614

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2435015614

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.08.18.255935