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Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroel...

Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2472181290

Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option

About this item

Full title

Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2020-12, Vol.52 (12), p.1294-1302

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and a regulator of several physiological processes.
ACE2
has recently been proposed to be interferon (IFN) inducible, suggesting that SARS-CoV-2 may exploit this phenomenon to enhance viral spread and questioning the ef...

Alternative Titles

Full title

Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2472181290

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2472181290

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-020-00732-8

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