In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibi...
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract The humoral immune response plays a key role in suppressing the pathogenesis of SARS-CoV-2. The molecular determinants underlying the neutralization of the virus remain, however, incompletely understood. Here, we show that the ability of antibodies to disrupt the binding of the viral spike protein to the angiotensin-converting enzyme 2 (AC...
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In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
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TN_cdi_proquest_journals_2506025506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506025506
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2692-8205
DOI
10.1101/2020.12.20.422820
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https://www.proquest.com/docview/2506025506?pq-origsite=primo&accountid=13902