Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS
Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Mitochondrial defects are a common hallmark of familial and sporadic forms of amyotrophic lateral sclerosis (ALS). However, the origin of these defects, including reduced pyruvate metabolism and reduced oxygen consumption, is poorly understood. These metabolic functions are regulated in specialized endoplasmic reticulum (ER) domains in close contac...
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Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS
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TN_cdi_proquest_journals_2716765089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2716765089
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E-ISSN
2692-8205
DOI
10.1101/2022.09.22.508778
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https://www.proquest.com/docview/2716765089?pq-origsite=primo&accountid=13902
