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Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Pa...

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Pa...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2785833606

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

About this item

Full title

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-12

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The classical diagnosis of Parkinsonism is based on motor symptoms that are the consequence of nigrostriatal pathway dysfunction and reduced dopaminergic output. However, a decade prior to the emergence of motor issues, patients frequently experience non-motor symptoms, such as a reduced sense of smell (hyposmia). The cellular and molecular bases f...

Alternative Titles

Full title

Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2785833606

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2785833606

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.03.11.532176