Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle proge...
Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation
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Author / Creator
Youssef, Khalil Kass , Lapouge, Gaëlle , Bouvrée, Karine , Rorive, Sandrine , Brohée, Sylvain , Appelstein, Ornella , Larsimont, Jean-Christophe , Sukumaran, Vijayakumar , Van de Sande, Bram , Pucci, Doriana , Dekoninck, Sophie , Berthe, Jean-Valery , Aerts, Stein , Salmon, Isabelle , del Marmol, Véronique and Blanpain, Cédric
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Basal cell carcinoma, the most frequent human skin cancer, arises from activating hedgehog (HH) pathway mutations; however, little is known about the temporal changes that occur in tumour-initiating cells from the first oncogenic hit to the development of invasive cancer. Using an inducible mouse model enabling the expression of a constitutively ac...
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Full title
Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation
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TN_cdi_proquest_miscellaneous_1221134060
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1221134060
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2628
