Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 tri...
Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial
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for the ATAMS Study Group , ATAMS Study Group , Kappos, Ludwig, Prof , Hartung, Hans-Peter, Prof , Freedman, Mark S, Prof , Boyko, Alexey, Prof , Radü, Ernst Wilhelm, Prof , Mikol, Daniel D, MD , Lamarine, Marc, PhD , Hyvert, Yann, PhD , Freudensprung, Ulrich, MS , Plitz, Thomas, PhD and van Beek, Johan, PhD
Publisher
England: Elsevier Ltd
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Language
English
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England: Elsevier Ltd
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Summary Background Depletion of B lymphocytes is associated with suppression of inflammatory activity in multiple sclerosis. We aimed to assess the safety and efficacy of atacicept, a recombinant fusion protein that suppresses B-cell function and antibody production. Methods In this placebo-controlled, double-blind, 36-week, phase 2 trial (ATAMS) i...
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Full title
Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial
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TN_cdi_proquest_miscellaneous_1512322268
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1512322268
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ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(14)70028-6