Allosteric targeting of receptor tyrosine kinases
Allosteric targeting of receptor tyrosine kinases
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
The drug discovery landscape has been transformed over the past decade by the discovery of allosteric modulators of all major mammalian receptor superfamilies. Allosteric ligands are a rich potential source of drugs and drug targets with clear therapeutic advantages. G protein–coupled receptors, ligand-gated ion channels and intracellular nuclear h...
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Full title
Allosteric targeting of receptor tyrosine kinases
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TN_cdi_proquest_miscellaneous_1664213126
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664213126
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.3028