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Allosteric targeting of receptor tyrosine kinases

Allosteric targeting of receptor tyrosine kinases

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664213126

Allosteric targeting of receptor tyrosine kinases

About this item

Full title

Allosteric targeting of receptor tyrosine kinases

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2014-11, Vol.32 (11), p.1113-1120

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The drug discovery landscape has been transformed over the past decade by the discovery of allosteric modulators of all major mammalian receptor superfamilies. Allosteric ligands are a rich potential source of drugs and drug targets with clear therapeutic advantages. G protein–coupled receptors, ligand-gated ion channels and intracellular nuclear h...

Alternative Titles

Full title

Allosteric targeting of receptor tyrosine kinases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1664213126

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1664213126

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.3028

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