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Controlling epithelial sodium channels with light using photoswitchable amilorides

Controlling epithelial sodium channels with light using photoswitchable amilorides

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727679956

Controlling epithelial sodium channels with light using photoswitchable amilorides

About this item

Full title

Controlling epithelial sodium channels with light using photoswitchable amilorides

Publisher

London: Nature Publishing Group UK

Journal title

Nature chemistry, 2014-08, Vol.6 (8), p.712-719

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Amiloride is a widely used diuretic that blocks epithelial sodium channels (ENaCs). These heterotrimeric transmembrane proteins, assembled from β, γ and α or δ subunits, effectively control water transport across epithelia and sodium influx into non-epithelial cells. The functional role of δβγENaC in various organs, including the human brain, is st...

Alternative Titles

Full title

Controlling epithelial sodium channels with light using photoswitchable amilorides

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1727679956

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727679956

Other Identifiers

ISSN

1755-4330

E-ISSN

1755-4349

DOI

10.1038/nchem.2004

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