YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers: e1005465
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers: e1005465
About this item
Full title
Author / Creator
Publisher
San Francisco: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
San Francisco: Public Library of Science
Subjects
More information
Scope and Contents
Contents
YAP1 is a major effector of the Hippo pathway and a well-established oncogene. Elevated YAP1 activity due to mutations in Hippo pathway components or YAP1 amplification is observed in several types of human cancers. Here we investigated its genomic binding landscape in YAP1-activated cancer cells, as well as in non-transformed cells. We demonstrate...
Alternative Titles
Full title
YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers: e1005465
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1727684236
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1727684236
Other Identifiers
ISSN
1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1005465
