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Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768570285

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

About this item

Full title

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2016-02, Vol.34 (8), p.1025-1033

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights • Borrelial lipoprotein OspA loses its outer-surface localization in Neisseria. • Surface-display rescued by fusion to part of meningococcal surface-lipoprotein fHbp. • OMVs with surface-exposed OspA elicit OspA-specific antibody responses in mice. • New method for surface display of heterologous lipoproteins in OMVs.

Alternative Titles

Full title

Surface display of a borrelial lipoprotein on meningococcal outer membrane vesicles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1768570285

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768570285

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2016.01.019

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