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Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FU...

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FU...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1776662084

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS

About this item

Full title

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2016-04, Vol.131 (4), p.587-604

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Deposition of the nuclear DNA/RNA-binding protein Fused in sarcoma (FUS) in cytosolic inclusions is a common hallmark of some cases of frontotemporal lobar degeneration (FTLD-FUS) and amyotrophic lateral sclerosis (ALS-
FUS
). Whether both diseases also share common pathological mechanisms is currently unclear. Based on our previous finding t...

Alternative Titles

Full title

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1776662084

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1776662084

Other Identifiers

ISSN

0001-6322

E-ISSN

1432-0533

DOI

10.1007/s00401-016-1544-2

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