Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration
Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration
About this item
Full title
Author / Creator
Sun, Yue , Xue, Weili , Song, Zhiyin , Huang, Kun and Zheng, Ling
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Optic atrophy 1 (Opa1) is a critical factor that regulates fusion and other important functions of mitochondria. In mitochondrion, the N-terminal mitochondrial targeting sequence of Opa1 precursors is removed to generate Opa1 long isoforms (L-Opa1), which are further cleaved into short isoforms (S-Opa1). In the present study, we found that retinal...
Alternative Titles
Full title
Restoration of Opa1-long isoform inhibits retinal injury-induced neurodegeneration
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1780532790
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1780532790
Other Identifiers
ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-015-1359-y
