Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated effic...
Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial
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Author / Creator
Ascierto, Paolo A , McArthur, Grant A , Dréno, Brigitte , Atkinson, Victoria , Liszkay, Gabrielle , Di Giacomo, Anna Maria , Mandalà, Mario , Demidov, Lev , Stroyakovskiy, Daniil , Thomas, Luc , de la Cruz-Merino, Luis , Dutriaux, Caroline , Garbe, Claus , Yan, Yibing , Wongchenko, Matthew , Chang, Ilsung , Hsu, Jessie J , Koralek, Daniel O , Rooney, Isabelle , Ribas, Antoni and Larkin, James
Publisher
England
Journal title
Language
English
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Publication information
Publisher
England
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Scope and Contents
Contents
The combination of cobimetinib with vemurafenib improves progression-free survival compared with placebo and vemurafenib in previously untreated patients with BRAF(V600)-mutant advanced melanoma, as previously reported in the coBRIM study. In this Article, we report updated efficacy results, including overall survival and safety after longer follow...
Alternative Titles
Full title
Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial
Authors, Artists and Contributors
Author / Creator
McArthur, Grant A
Dréno, Brigitte
Atkinson, Victoria
Liszkay, Gabrielle
Di Giacomo, Anna Maria
Mandalà, Mario
Demidov, Lev
Stroyakovskiy, Daniil
Thomas, Luc
de la Cruz-Merino, Luis
Dutriaux, Caroline
Garbe, Claus
Yan, Yibing
Wongchenko, Matthew
Chang, Ilsung
Hsu, Jessie J
Koralek, Daniel O
Rooney, Isabelle
Ribas, Antoni
Larkin, James
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1817854525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1817854525
Other Identifiers
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(16)30122-X