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Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
Author / Creator:Robert, Caroline ; Grob, Jean J ; Stroyakovskiy, Daniil ; Karaszewska, Boguslawa ; Hauschild, Axel ; Levchenko, Evgeny ; Chiarion Sileni, Vanna ; Schachter, Jacob ; Garbe, Claus ; Bondarenko, Igor ; Gogas, Helen ; Mandalá, Mario ; Haanen, John B.A.G ; Lebbé, Celeste ; Mackiewicz, Andrzej ; Rutkowski, Piotr ; Nathan, Paul D ; Ribas, Antoni ; Davies, Michael A ; Flaherty, Keith T ; Burgess, Paul ; Tan, Monique ; Gasal, Eduard ; Voi, Maurizio ; Schadendorf, Dirk ; Long, Georgina V
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-08, Vol.381 (7), p.626-636
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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer
Author / Creator:Prager, Gerald W. ; Taieb, Julien ; Fakih, Marwan ; Ciardiello, Fortunato ; Van Cutsem, Eric ; Elez, Elena ; Cruz, Felipe M. ; Wyrwicz, Lucjan ; Stroyakovskiy, Daniil ; Pápai, Zsuzsanna ; Poureau, Pierre-Guillaume ; Liposits, Gabor ; Cremolini, Chiara ; Bondarenko, Igor ; Modest, Dominik P. ; Benhadji, Karim A. ; Amellal, Nadia ; Leger, Catherine ; Vidot, Loïck ; Tabernero, Josep
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-05, Vol.388 (18), p.1657-1667
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Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma
Author / Creator:Larkin, James ; Ascierto, Paolo A ; Dréno, Brigitte ; Atkinson, Victoria ; Liszkay, Gabriella ; Maio, Michele ; Mandalà, Mario ; Demidov, Lev ; Stroyakovskiy, Daniil ; Thomas, Luc ; de la Cruz-Merino, Luis ; Dutriaux, Caroline ; Garbe, Claus ; Sovak, Mika A ; Chang, Ilsung ; Choong, Nicholas ; Hack, Stephen P ; McArthur, Grant A ; Ribas, Antoni
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-11, Vol.371 (20), p.1867-1876
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Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase...
Author / Creator:Hurvitz, Sara A, MD ; Martin, Miguel, Prof ; Symmans, W Fraser, Prof ; Jung, Kyung Hae, Prof ; Huang, Chiun-Sheng, Prof ; Thompson, Alastair M, Prof ; Harbeck, Nadia, Prof ; Valero, Vicente, Prof ; Stroyakovskiy, Daniil, MD ; Wildiers, Hans, Prof ; Campone, Mario, Prof ; Boileau, Jean-François, MD ; Beckmann, Matthias W, Prof ; Afenjar, Karen, MS ; Fresco, Rodrigo, MD ; Helms, Hans-Joachim, PhD ; Xu, Jin, PhD ; Lin, Yvonne G, MD ; Sparano, Joseph, Prof ; Slamon, Dennis, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018, Vol.19 (1), p.115-126
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Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAFV600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, ra...
Author / Creator:Ascierto, Paolo A, Prof ; Stroyakovskiy, Daniil, MD ; Gogas, Helen, Prof ; Robert, Caroline, Prof ; Lewis, Karl, Prof ; Protsenko, Svetlana, MD ; Pereira, Rodrigo P, MD ; Eigentler, Thomas, MD ; Rutkowski, Piotr, MD ; Demidov, Lev, MD ; Zhukova, Natalia, PhD ; Schachter, Jacob, Prof ; Yan, Yibing, PhD ; Caro, Ivor, MD ; Hertig, Christian, DVM ; Xue, Cloris, MSc ; Kusters, Lieke, MSc ; McArthur, Grant A, Prof ; Gutzmer, Ralf, Prof
Publisher:Elsevier Ltd
Journal title:The lancet oncology, 2023-01, Vol.24 (1), p.33-44
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Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-po...
Author / Creator:Grob, Jean Jacques, Prof ; Amonkar, Mayur M, PhD ; Karaszewska, Boguslawa, MD ; Schachter, Jacob, Prof ; Dummer, Reinhard, Prof ; Mackiewicz, Andrzej, Prof ; Stroyakovskiy, Daniil, MD ; Drucis, Kamil, MD ; Grange, Florent, MD ; Chiarion-Sileni, Vanna, MD ; Rutkowski, Piotr, Prof ; Lichinitser, Mikhail, Prof ; Levchenko, Evgeny, MD ; Wolter, Pascal, MD ; Hauschild, Axel, Prof ; Long, Georgina V, MD ; Nathan, Paul, MD ; Ribas, Antoni, Prof ; Flaherty, Keith, MD ; Sun, Peng, PhD ; Legos, Jeffrey J, PhD ; McDowell, Diane Opatt, MD ; Mookerjee, Bijoyesh, MD ; Schadendorf, Dirk, Prof ; Robert, Caroline, MD
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2015-10, Vol.16 (13), p.1389-1398
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Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib + endocrine therapy versus endocrine therapy alone in patients with HR+/HER2− early breast cancer
Author / Creator:Slamon, Dennis J. ; Fasching, Peter A. ; Hurvitz, Sara ; Chia, Stephen ; Crown, John ; Martín, Miguel ; Barrios, Carlos H. ; Bardia, Aditya ; Im, Seock-Ah ; Yardley, Denise A. ; Untch, Michael ; Huang, Chiun-Sheng ; Stroyakovskiy, Daniil ; Xu, Binghe ; Moroose, Rebecca L. ; Loi, Sherene ; Visco, Frances ; Bee-Munteanu, Valerie ; Afenjar, Karen ; Fresco, Rodrigo ; Taran, Tetiana ; Chakravartty, Arunava ; Zarate, Juan Pablo ; Lteif, Agnes ; Hortobagyi, Gabriel N.
Publisher:London, England: SAGE Publications
Journal title:Therapeutic advances in medical oncology, 2023-01, Vol.15, p.17588359231178125-17588359231178125
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Randomized double-blind clinical trial comparing safety and efficacy of the biosimilar BCD-021 with reference bevacizumab
Author / Creator:Stroyakovskiy, Daniil L ; Fadeeva, Natalya V ; Matrosova, Marina P ; Shelepen, Konstantin G ; Adamchuk, Grigoriy A ; Roy, Bodhisatta ; Nagarkar, Rajnish ; Kalloli, Mahesh ; Zhuravleva, Daria ; Voevodin, Georgiy D ; Shustova, Mariya S ; Kryukov, Fedor
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2022-02, Vol.22 (1), p.129-129, Article 129
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Real-World Experience with Targeted Therapy in BRAF Mutant Advanced Melanoma Patients: Results from a Multicenter Retrospective Observational Study Advanced Melanoma in Russia (Experience) (ADMIRE)
Author / Creator:Orlova, Kristina V. ; Ledin, Evgeniy V. ; Zhukova, Natalia V. ; Orlova, Rashida V. ; Karabina, Elena V. ; Volkonskiy, Mikhail V. ; Stroyakovskiy, Daniil L. ; Yurchenkov, Aleksandr N. ; Protsenko, Svetlana A. ; Novik, Alexey V. ; Vorotilina, Ludmila V. ; Moiseenko, Fedor V. ; Chang, Victor L. ; Kazmin, Aleksandr I. ; Tkachenko, Svetlana A. ; Gamaunov, Sergey V. ; Naskhletashvili, David R. ; Samoylenko, Igor V. ; Vikhrova, Anastasia S. ; Utyashev, Igor A. ; Kharkevich, Galina Yu ; Petenko, Natalia N. ; Shubina, Irina Zh ; Demidov, Lev V.
Publisher:Basel: MDPI AG
Journal title:Cancers, 2021-05, Vol.13 (11), p.2529
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Cobimetinib combined with vemurafenib in advanced BRAFV600 -mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial
Author / Creator:Ascierto, Paolo A, MD ; McArthur, Grant A, Prof ; Dréno, Brigitte, Prof ; Atkinson, Victoria, MD ; Liszkay, Gabrielle, MD ; Di Giacomo, Anna Maria, MD ; Mandalà, Mario, MD ; Demidov, Lev, MD ; Stroyakovskiy, Daniil, MD ; Thomas, Luc, Prof ; de la Cruz-Merino, Luis, MD ; Dutriaux, Caroline, MD ; Garbe, Claus, Prof ; Yan, Yibing, PhD ; Wongchenko, Matthew, BS ; Chang, Ilsung, PhD ; Hsu, Jessie J, PhD ; Koralek, Daniel O, PhD ; Rooney, Isabelle, MBChB ; Ribas, Antoni, Prof ; Larkin, James, FRCP
Publisher:London: Elsevier Ltd
Journal title:The lancet oncology, 2016-09, Vol.17 (9), p.1248-1260
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301 Association of response with survival outcomes with atezolizumab in combination with vemurafenib and cobimetinib in the phase 3 IMspire150 study
Author / Creator:Ascierto, Paolo ; Lewis, Karl ; Robert, Caroline ; Stroyakovskiy, Daniil ; Gogas, Helen ; Protsenko, Svetlana ; Pereira, Rodrigo ; Eigentler, Thomas ; Rutkowski, Piotr ; Demidov, Lev ; Manikhas, Georgy Moiseevich ; Li, Haocheng ; Zhu, Qian ; McKenna, Edward ; McNally, Virginia ; Gutzmer, Ralf ; McArthur, Grant
Publisher:London: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A328-A328
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Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial
Author / Creator:Ascierto, Paolo A ; McArthur, Grant A ; Dréno, Brigitte ; Atkinson, Victoria ; Liszkay, Gabrielle ; Di Giacomo, Anna Maria ; Mandalà, Mario ; Demidov, Lev ; Stroyakovskiy, Daniil ; Thomas, Luc ; de la Cruz-Merino, Luis ; Dutriaux, Caroline ; Garbe, Claus ; Yan, Yibing ; Wongchenko, Matthew ; Chang, Ilsung ; Hsu, Jessie J ; Koralek, Daniel O ; Rooney, Isabelle ; Ribas, Antoni ; Larkin, James
Publisher:England
Journal title:The lancet oncology, 2016-09, Vol.17 (9), p.1248-1260
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Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial
Author / Creator:Sweeney, Christopher ; Bracarda, Sergio ; Sternberg, Cora N ; Chi, Kim N ; Olmos, David ; Sandhu, Shahneen ; Massard, Christophe ; Matsubara, Nobuaki ; Alekseev, Boris ; Parnis, Francis ; Atduev, Vagif ; Buchschacher, Gary L ; Gafanov, Rustem ; Corrales, Luis ; Borre, Michael ; Stroyakovskiy, Daniil ; Alves, Gustavo Vasconcelos ; Bournakis, Evangelos ; Puente, Javier ; Harle-Yge, Marie-Laurence ; Gallo, Jorge ; Chen, Geng ; Hanover, Justin ; Wongchenko, Matthew J ; Garcia, Josep ; de Bono, Johann S
Publisher:London: Elsevier Ltd
Journal title:The Lancet (British edition), 2021-07, Vol.398 (10295), p.131-142
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Ribociclib plus Endocrine Therapy in Early Breast Cancer
Author / Creator:Slamon, Dennis ; Lipatov, Oleg ; Nowecki, Zbigniew ; McAndrew, Nicholas ; Kukielka-Budny, Bozena ; Stroyakovskiy, Daniil ; Yardley, Denise A. ; Huang, Chiun-Sheng ; Fasching, Peter A. ; Crown, John ; Bardia, Aditya ; Chia, Stephen ; Im, Seock-Ah ; Ruiz-Borrego, Manuel ; Loi, Sherene ; Xu, Binghe ; Hurvitz, Sara ; Barrios, Carlos ; Untch, Michael ; Moroose, Rebecca ; Visco, Frances ; Afenjar, Karen ; Fresco, Rodrigo ; Severin, Irene ; Ji, Yan ; Ghaznawi, Farhat ; Li, Zheng ; Zarate, Juan P. ; Chakravartty, Arunava ; Taran, Tetiana ; Hortobagyi, Gabriel
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-03, Vol.390 (12), p.1080-1091
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Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial
Author / Creator:Long, Georgina V, MD ; Stroyakovskiy, Daniil, MD ; Gogas, Helen, MD ; Levchenko, Evgeny, MD ; de Braud, Filippo, MD ; Larkin, James, FRCP ; Garbe, Claus, Prof ; Jouary, Thomas, MD ; Hauschild, Axel, Prof ; Grob, Jean-Jacques, Prof ; Chiarion-Sileni, Vanna, MD ; Lebbe, Celeste, Prof ; Mandalà, Mario, MD ; Millward, Michael, Prof ; Arance, Ana, MD ; Bondarenko, Igor, Prof ; Haanen, John B A G, Prof ; Hansson, Johan, Prof ; Utikal, Jochen, Prof ; Ferraresi, Virginia, MD ; Kovalenko, Nadezhda, Prof ; Mohr, Peter, MD ; Probachai, Volodymr, MD ; Schadendorf, Dirk, Prof ; Nathan, Paul, MD ; Robert, Caroline, MD ; Ribas, Antoni, Prof ; DeMarini, Douglas J, PhD ; Irani, Jhangir G, MA ; Swann, Suzanne, PhD ; Legos, Jeffrey J, PhD ; Jin, Fan, MD ; Mookerjee, Bijoyesh, MD ; Flaherty, Keith, MD
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2015-08, Vol.386 (9992), p.444-451
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Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma
Author / Creator:Long, Georgina V ; Stroyakovskiy, Daniil ; Gogas, Helen ; Levchenko, Evgeny ; de Braud, Filippo ; Larkin, James ; Garbe, Claus ; Jouary, Thomas ; Hauschild, Axel ; Grob, Jean Jacques ; Chiarion Sileni, Vanna ; Lebbe, Celeste ; Mandalà, Mario ; Millward, Michael ; Arance, Ana ; Bondarenko, Igor ; Haanen, John B.A.G ; Hansson, Johan ; Utikal, Jochen ; Ferraresi, Virginia ; Kovalenko, Nadezhda ; Mohr, Peter ; Probachai, Volodymyr ; Schadendorf, Dirk ; Nathan, Paul ; Robert, Caroline ; Ribas, Antoni ; DeMarini, Douglas J ; Irani, Jhangir G ; Casey, Michelle ; Ouellet, Daniele ; Martin, Anne-Marie ; Le, Ngocdiep ; Patel, Kiran ; Flaherty, Keith
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-11, Vol.371 (20), p.1877-1888
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Amivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC
Author / Creator:Cho, Byoung C. ; Lu, Shun ; Felip, Enriqueta ; Spira, Alexander I. ; Girard, Nicolas ; Lee, Jong-Seok ; Lee, Se-Hoon ; Ostapenko, Yurii ; Danchaivijitr, Pongwut ; Liu, Baogang ; Alip, Adlinda ; Korbenfeld, Ernesto ; Mourão Dias, Josiane ; Besse, Benjamin ; Lee, Ki-Hyeong ; Xiong, Hailin ; How, Soon-Hin ; Cheng, Ying ; Chang, Gee-Chen ; Yoshioka, Hiroshige ; Yang, James C.-H. ; Thomas, Michael ; Nguyen, Danny ; Ou, Sai-Hong I. ; Mukhedkar, Sanjay ; Prabhash, Kumar ; D’Arcangelo, Manolo ; Alatorre-Alexander, Jorge ; Vázquez Limón, Juan C. ; Alves, Sara ; Stroyakovskiy, Daniil ; Peregudova, Marina ; Şendur, Mehmet A.N. ; Yazici, Ozan ; Califano, Raffaele ; Gutiérrez Calderón, Vanesa ; de Marinis, Filippo ; Passaro, Antonio ; Kim, Sang-We ; Gadgeel, Shirish M. ; Xie, John ; Sun, Tao ; Martinez, Melissa ; Ennis, Mariah ; Fennema, Elizabeth ; Daksh, Mahesh ; Millington, Dawn ; Leconte, Isabelle ; Iwasawa, Ryota ; Lorenzini, Patricia ; Baig, Mahadi ; Shah, Sujay ; Bauml, Joshua M. ; Shreeve, S. Martin ; Sethi, Seema ; Knoblauch, Roland E. ; Hayashi, Hidetoshi
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2024-10, Vol.391 (16), p.1486-1498
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Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAF V600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, r...
Author / Creator:Ascierto, Paolo A ; Stroyakovskiy, Daniil ; Gogas, Helen ; Robert, Caroline ; Lewis, Karl ; Protsenko, Svetlana ; Pereira, Rodrigo P ; Eigentler, Thomas ; Rutkowski, Piotr ; Demidov, Lev ; Zhukova, Natalia ; Schachter, Jacob ; Yan, Yibing ; Caro, Ivor ; Hertig, Christian ; Xue, Cloris ; Kusters, Lieke ; McArthur, Grant A ; Gutzmer, Ralf
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2023-01, Vol.24 (1), p.33
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Health-Related Quality of Life Outcomes With Two Different Starting Doses of Lenvatinib in Combination With Everolimus for Previously Treated Renal Cell Carcinoma
Author / Creator:Bergerot, Cristiane ; Young Rha, Sun ; Pal, Sumanta ; Koralewski, Piotr ; Stroyakovskiy, Daniil ; Alekseev, Boris ; Parnis, Francis ; Castellano, Daniel ; Lyun Lee, Jae ; Sunela, Kaisa ; Ciuleanu, Tudor ; Heng, Daniel ; Glen, Hilary ; Wang, Jinyi ; Bennett, Lee ; Pan, Janice ; O’Hara, Karen ; Puente, Javier
Publisher:US: Oxford University Press
Journal title:The oncologist (Dayton, Ohio), 2023-01, Vol.28 (1), p.59-71
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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo...
Author / Creator:Gutzmer, Ralf ; Stroyakovskiy, Daniil ; Gogas, Helen ; Robert, Caroline ; Lewis, Karl ; Protsenko, Svetlana ; Pereira, Rodrigo P ; Eigentler, Thomas ; Rutkowski, Piotr ; Demidov, Lev ; Manikhas, Georgy Moiseevich ; Yan, Yibing ; Huang, Kuan-Chieh ; Uyei, Anne ; McNally, Virginia ; McArthur, Grant A ; Ascierto, Paolo A
Publisher:Elsevier Ltd
Journal title:The Lancet (British edition), 2020-06, Vol.395 (10240), p.1835-1844
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Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma

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Trifluridine–Tipiracil and Bevacizumab in Refractory Metastatic Colorectal Cancer

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Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma

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Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase...

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Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAFV600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, ra...

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Comparison of dabrafenib and trametinib combination therapy with vemurafenib monotherapy on health-related quality of life in patients with unresectable or metastatic cutaneous BRAF Val600-mutation-po...

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Rationale and trial design of NATALEE: a Phase III trial of adjuvant ribociclib + endocrine therapy versus endocrine therapy alone in patients with HR+/HER2− early breast cancer

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Randomized double-blind clinical trial comparing safety and efficacy of the biosimilar BCD-021 with reference bevacizumab

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Real-World Experience with Targeted Therapy in BRAF Mutant Advanced Melanoma Patients: Results from a Multicenter Retrospective Observational Study Advanced Melanoma in Russia (Experience) (ADMIRE)

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Cobimetinib combined with vemurafenib in advanced BRAFV600 -mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial

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301 Association of response with survival outcomes with atezolizumab in combination with vemurafenib and cobimetinib in the phase 3 IMspire150 study

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Cobimetinib combined with vemurafenib in advanced BRAF(V600)-mutant melanoma (coBRIM): updated efficacy results from a randomised, double-blind, phase 3 trial

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Ipatasertib plus abiraterone and prednisolone in metastatic castration-resistant prostate cancer (IPATential150): a multicentre, randomised, double-blind, phase 3 trial

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Ribociclib plus Endocrine Therapy in Early Breast Cancer

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Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial

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Combined BRAF and MEK Inhibition versus BRAF Inhibition Alone in Melanoma

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Amivantamab plus Lazertinib in Previously Untreated EGFR-Mutated Advanced NSCLC

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Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAF V600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, r...

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Health-Related Quality of Life Outcomes With Two Different Starting Doses of Lenvatinib in Combination With Everolimus for Previously Treated Renal Cell Carcinoma

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Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo...

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