A developmental coordinate of pluripotency among mice, monkeys and humans
A developmental coordinate of pluripotency among mice, monkeys and humans
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The epiblast (EPI) is the origin of all somatic and germ cells in mammals, and of pluripotent stem cells
in vitro
. To explore the ontogeny of human and primate pluripotency, here we perform comprehensive single-cell RNA sequencing for pre- and post-implantation EPI development in cynomolgus monkeys (
Macaca fascicularis
). We show that...
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A developmental coordinate of pluripotency among mice, monkeys and humans
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TN_cdi_proquest_miscellaneous_1852656154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1852656154
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature19096