Allelic reprogramming of 3D chromatin architecture during early mammalian development
Allelic reprogramming of 3D chromatin architecture during early mammalian development
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Author / Creator
Du, Zhenhai , Zheng, Hui , Huang, Bo , Ma, Rui , Wu, Jingyi , Zhang, Xianglin , He, Jing , Xiang, Yunlong , Wang, Qiujun , Li, Yuanyuan , Ma, Jing , Zhang, Xu , Zhang, Ke , Wang, Yang , Zhang, Michael Q. , Gao, Juntao , Dixon, Jesse R. , Wang, Xiaowo , Zeng, Jianyang and Xie, Wei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
A low-input Hi-C method is used to show that chromatin organization is markedly relaxed in pre-implantation mouse embryos after fertilization and that the subsequent maturation of 3D chromatin architecture is surprisingly slow.
Early development chromatin reorganization
In mammals, chromatin undergoes reorganization after fertilization, but l...
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Full title
Allelic reprogramming of 3D chromatin architecture during early mammalian development
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TN_cdi_proquest_miscellaneous_1918845332
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1918845332
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature23263