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Genetic and transcriptional landscape of plasma cells in POEMS syndrome

Genetic and transcriptional landscape of plasma cells in POEMS syndrome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179367083

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

POEMS syndrome is a rare paraneoplastic disease associated with monoclonal plasma cells; however, the pathogenic importance of plasma cells remains unclear. We performed comprehensive genetic analyses of plasma cells in 20 patients with POEMS syndrome. Whole exome sequencing was performed in 11 cases and found a total of 308 somatic mutations in 28...

Alternative Titles

Full title

Genetic and transcriptional landscape of plasma cells in POEMS syndrome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2179367083

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179367083

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/s41375-018-0348-x

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