Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
About this item
Full title
Author / Creator
Robert, Caroline , Grob, Jean J , Stroyakovskiy, Daniil , Karaszewska, Boguslawa , Hauschild, Axel , Levchenko, Evgeny , Chiarion Sileni, Vanna , Schachter, Jacob , Garbe, Claus , Bondarenko, Igor , Gogas, Helen , Mandalá, Mario , Haanen, John B.A.G , Lebbé, Celeste , Mackiewicz, Andrzej , Rutkowski, Piotr , Nathan, Paul D , Ribas, Antoni , Davies, Michael A , Flaherty, Keith T , Burgess, Paul , Tan, Monique , Gasal, Eduard , Voi, Maurizio , Schadendorf, Dirk and Long, Georgina V
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In long-term follow-up of more than 500 patients with melanoma containing a
BRAF
V600E or V600K mutation, a combination of dabrafenib plus trametinib was associated with progression-free survival in 19% of the patients and overall survival in 34% at 5 years. A complete response to dabrafenib plus trametinib was the strongest predictor of long...
Alternative Titles
Full title
Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
Authors, Artists and Contributors
Author / Creator
Grob, Jean J
Stroyakovskiy, Daniil
Karaszewska, Boguslawa
Hauschild, Axel
Levchenko, Evgeny
Chiarion Sileni, Vanna
Schachter, Jacob
Garbe, Claus
Bondarenko, Igor
Gogas, Helen
Mandalá, Mario
Haanen, John B.A.G
Lebbé, Celeste
Mackiewicz, Andrzej
Rutkowski, Piotr
Nathan, Paul D
Ribas, Antoni
Davies, Michael A
Flaherty, Keith T
Burgess, Paul
Tan, Monique
Gasal, Eduard
Voi, Maurizio
Schadendorf, Dirk
Long, Georgina V
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2273766258
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2273766258
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1904059
