Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs
Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs
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Author / Creator
Chen, Xianjun , Zhang, Dasheng , Su, Ni , Bao, Bingkun , Xie, Xin , Zuo, Fangting , Yang, Lipeng , Wang, Hui , Jiang, Li , Lin, Qiuning , Fang, Mengyue , Li, Ningfeng , Hua, Xin , Chen, Zhengda , Bao, Chunyan , Xu, Jinjin , Du, Wenli , Zhang, Lixin , Zhao, Yuzheng , Zhu, Linyong , Loscalzo, Joseph and Yang, Yi
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Fluorescent RNAs (FRs), aptamers that bind and activate fluorescent dyes, have been used to image abundant cellular RNA species. However, limitations such as low brightness and limited availability of dye/aptamer combinations with different spectral characteristics have limited use of these tools in live mammalian cells and in vivo. Here, we develo...
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Full title
Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs
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TN_cdi_proquest_miscellaneous_2296666222
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2296666222
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-019-0249-1