COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-ce...
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
About this item
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Author / Creator
Chua, Robert Lorenz , Lukassen, Soeren , Trump, Saskia , Hennig, Bianca P. , Wendisch, Daniel , Pott, Fabian , Debnath, Olivia , Thürmann, Loreen , Kurth, Florian , Völker, Maria Theresa , Kazmierski, Julia , Timmermann, Bernd , Twardziok, Sven , Schneider, Stefan , Machleidt, Felix , Müller-Redetzky, Holger , Maier, Melanie , Krannich, Alexander , Schmidt, Sein , Balzer, Felix , Liebig, Johannes , Loske, Jennifer , Suttorp, Norbert , Eils, Jürgen , Ishaque, Naveed , Liebert, Uwe Gerd , von Kalle, Christof , Hocke, Andreas , Witzenrath, Martin , Goffinet, Christine , Drosten, Christian , Laudi, Sven , Lehmann, Irina , Conrad, Christian , Sander, Leif-Erik and Eils, Roland
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
To investigate the immune response and mechanisms associated with severe coronavirus disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal and bronchial samples from 19 clinically well-characterized patients with moderate or critical disease and from five healthy controls. We identified airway epithelial cell types and...
Alternative Titles
Full title
COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis
Authors, Artists and Contributors
Author / Creator
Lukassen, Soeren
Trump, Saskia
Hennig, Bianca P.
Wendisch, Daniel
Pott, Fabian
Debnath, Olivia
Thürmann, Loreen
Kurth, Florian
Völker, Maria Theresa
Kazmierski, Julia
Timmermann, Bernd
Twardziok, Sven
Schneider, Stefan
Machleidt, Felix
Müller-Redetzky, Holger
Maier, Melanie
Krannich, Alexander
Schmidt, Sein
Balzer, Felix
Liebig, Johannes
Loske, Jennifer
Suttorp, Norbert
Eils, Jürgen
Ishaque, Naveed
Liebert, Uwe Gerd
von Kalle, Christof
Hocke, Andreas
Witzenrath, Martin
Goffinet, Christine
Drosten, Christian
Laudi, Sven
Lehmann, Irina
Conrad, Christian
Sander, Leif-Erik
Eils, Roland
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2418125773
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2418125773
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-020-0602-4
