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Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macr...

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2507145528

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

About this item

Full title

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2021-04, Vol.24 (4), p.595-610

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Glioblastomas are aggressive primary brain cancers that recur as therapy-resistant tumors. Myeloid cells control glioblastoma malignancy, but their dynamics during disease progression remain poorly understood. Here, we employed single-cell RNA sequencing and CITE-seq to map the glioblastoma immune landscape in mouse tumors and in patients with newl...

Alternative Titles

Full title

Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2507145528

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2507145528

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/s41593-020-00789-y

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